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(2E)-3-[4-(1H-Benzimidazol-2-ylmethoxy)-3-methoxyphenyl]-1-(4,4''-difluoro-5'-methoxy-1,1':3',1''-terphenyl-4'-yl)prop-2-en-1-one
Molbank 2012, 2012(3), M765; doi:10.3390/M765
Short Note

2-Methoxy-5-{4-oxo-2-[(E)-2-(4-sulfamoylphenyl)ethenyl-3,4-dihydroquinazolin-3-yl]benzene-1-sulfonamide

1,* , 2, 1 and 3
1 Department of Pharmacy, Faculty of Natural Sciences, University of Indonesia, Depok, 16424, West Java, Indonesia 2 Research Center for Chemistry, Indonesian Institute of Sciences, Serpong, 15314, Indonesia 3 Department of Chemistry, Faculty of Natural Sciences, University of Indonesia, Depok, 16424, West Java, Indonesia
* Author to whom correspondence should be addressed.
Received: 2 May 2012 / Accepted: 11 July 2012 / Published: 18 July 2012
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Abstract

The title compound, 2-methoxy-5-{4-oxo-2-[(E)-2-(4-sulfamoylphenyl) ethenyl-3, 4-dihydroquinazolin-3-yl] benzene-1-sulfonamide 2 has been synthesized by the reaction of 3-(4-methoxyphenyl)-2-styryl-4(3H)-quinazolinone 1 with an excess of chlorosulfonic acid, followed by amidation of the sulfonyl chloride product with ammonia gas. The structure of the synthesized compound was confirmed on the basis of IR, 1H-NMR, 13C-NMR and mass spectral data.
Keywords: 4(3H)-quinazolinone; 2-styryl-4(3H)-quinazolinone; benzenesulfonamide; chlorosulfonation-amidation 4(3H)-quinazolinone; 2-styryl-4(3H)-quinazolinone; benzenesulfonamide; chlorosulfonation-amidation
This is an open access article distributed under the Creative Commons Attribution License (CC BY) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Hayun; Hanafi, M.; Yanuar, A.; Hudiyono, S. 2-Methoxy-5-{4-oxo-2-[(E)-2-(4-sulfamoylphenyl)ethenyl-3,4-dihydroquinazolin-3-yl]benzene-1-sulfonamide. Molbank 2012, 2012, M765.

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