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Sensors 2011, 11(12), 11036-11055; doi:10.3390/s111211036

Overview of Stabilizing Ligands for Biocompatible Quantum Dot Nanocrystals

Department of Chemical and Biological Engineering, Iowa State University, Ames, IA 50011, USA
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Author to whom correspondence should be addressed.
Received: 12 October 2011 / Revised: 21 November 2011 / Accepted: 22 November 2011 / Published: 28 November 2011
(This article belongs to the Special Issue Sensing with Quantum Dots)
View Full-Text   |   Download PDF [908 KB, uploaded 21 June 2014]   |  

Abstract

Luminescent colloidal quantum dots (QDs) possess numerous advantages as fluorophores in biological applications. However, a principal challenge is how to retain the desirable optical properties of quantum dots in aqueous media while maintaining biocompatibility. Because QD photophysical properties are directly related to surface states, it is critical to control the surface chemistry that renders QDs biocompatible while maintaining electronic passivation. For more than a decade, investigators have used diverse strategies for altering the QD surface. This review summarizes the most successful approaches for preparing biocompatible QDs using various chemical ligands. View Full-Text
Keywords: quantum dots; ligand; biocompatible quantum dots; ligand; biocompatible
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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Zhang, Y.; Clapp, A. Overview of Stabilizing Ligands for Biocompatible Quantum Dot Nanocrystals. Sensors 2011, 11, 11036-11055.

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