A New Spatane Diterpenoid from the Cultured Soft Coral Sinularia leptoclados
Abstract
A new spatane diterpenoid, leptoclalin A (1), along with two previously reported known norcembranoid diterpenes (2 and 3), were isolated from a cultured soft coral Sinularia leptoclados. The structures were determined by extensive spectroscopic analyses and by comparison with the spectral data of related known compounds. Metabolite 1 is rarely found in spatane skeletons reported from soft corals. In addition, compound 1 exhibited weak cytotoxicity towards human tumor cell lines T-47 D and K-562.Supplementary materials
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Tsai, T.-C.; Wu, Y.-J.; Su, J.-H.; Lin, W.-T.; Lin, Y.-S. A New Spatane Diterpenoid from the Cultured Soft Coral Sinularia leptoclados. Mar. Drugs 2013, 11, 114-123.