Differences and Similarities in Diabetes Research between China and the USA
Abstract
:1. Introduction
2. Methods
2.1. Inclusion and Exclusion Criteria
- Primary research studies or secondary analyses of routinely collected data or existing research datasets.
- Studies on diabetes research (e.g., risk factors, prognosis, prevention, diagnosis, treatment, and epidemiology).
- Studies conducted in mainland China or the USA.
- Studies published either in 2010 or 2015, in scientific journals, and with abstracts.
2.2. Study Search and Selection Strategy
2.3. Data Extraction and Analysis
3. Results
3.1. Main Characteristics of Included Studies
3.2. Relevance of the Included Studies
3.3. Type of Interventions
4. Discussion
5. Conclusions
Supplementary Materials
Author Contributions
Funding
Conflicts of Interest
Abbreviations
NCDs | Non-communicable diseases |
LMICs | Low and Middle Income Countries |
USA | United States of America |
RCTs | Randomized Controlled Trials |
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Countries of Authors | Published in 2010 | Published in 2015 | All | ||||
---|---|---|---|---|---|---|---|
China | USA | China | USA | China | USA | p | |
China | 200 (100%) | 0 (0%) | 187 (93.5%) | 0 (0%) | 387 (96.7%) | 0 (0%) | 0.000 * |
USA | 0 (0%) | 200 (100%) | 0 (0%) | 151 (75.5%) | 0 (0%) | 351 (87.7%) | |
Multiple | 0 (0%) | 0 (0%) | 13 (6.5%) | 49 (24.5%) | 13 (3.3%) | 49 (12.3%) | |
Publication language | |||||||
Chinese | 49 (24.5%) | 0 (0%) | 20 (10%) | 0 (0%) | 69 (17.3%) | 0 (0%) | 0.000 * |
English | 151 (75.5%) | 200 (100%) | 180 (90%) | 200 (100%) | 331 (82.7%) | 400 (100%) | |
Data source | |||||||
Primary | 190 (95%) | 139 (69.5%) | 194 (97%) | 164 (82%) | 384 (96%) | 303 (75.7%) | 0.000 * |
Secondary | 10 (5%) | 61 (30.5%) | 6 (3%) | 36 (18%) | 16 (4%) | 97 (24.3%) | |
Design | |||||||
Case series | 13 (6.5%) | 5 (2.5%) | 1 (0.5%) | 3 (1.5%) | 14 (3.5%) | 8 (2.0%) | 0.000 ** |
Case-control | 39 (19.5%) | 19 (9.5%) | 32 (16%) | 21 (10.5%) | 71 (17.7%) | 40 (10%) | |
Clinical trial | 14 (7%) | 25 (12.5%) | 11 (5.5%) | 33 (16.5%) | 25 (6.2%) | 58 (14.5%) | |
Cohort | 12 (6%) | 53 (26.5%) | 23 (11.5%) | 51 (25.5%) | 35 (8.8%) | 104 (26%) | |
Cross sectional | 24 (12%) | 37 (18.5%) | 29 (14.5%) | 30 (15%) | 53 (13.3%) | 67 (16.7%) | |
Laboratory-based | 98 (49%) | 61 (30.5%) | 104 (52%) | 62 (31%) | 202 (50.5%) | 123 (30.8%) | |
Study subjects | |||||||
Animal | 92 (46%) | 55 (27.5%) | 96 (48%) | 55 (27.5%) | 188 (47%) | 110 (27.5%) | 0.000 ** |
Bio-sample | 6 (3%) | 5 (2.5%) | 8 (4%) | 6 (3%) | 14 (3.5%) | 11 (2.7%) | |
Care providers | 0 (0%) | 4 (2%) | 0 (0%) | 1 (0.5%) | 0 (0%) | 5 (1.3%) | |
Patients | 86 (43%) | 120 (60%) | 85 (42.5%) | 123 (61.5%) | 171 (42.7%) | 243 (60.7%) | |
Population | 16 (8%) | 12 (6%) | 10 (5%) | 14 (7%) | 26 (6.5%) | 26 (6.5%) | |
Multiple | 0 (0%) | 3 (1.5%) | 1 (0.5%) | 1 (0.5%) | 1 (0.3%) | 4 (1%) | |
Other | 0 (0%) | 1 (0.5%) | 0 (0%) | 0 (0%) | 0 (0%) | 1 (0.3%) | |
Type of diabetes | |||||||
Type 1 and 2 | 191 (95.5%) | 172 (86%) | 162 (81%) | 171 (85.5%) | 353 (88.3%) | 343 (85.7%) | 0.221 * |
Gestational | 4 (2%) | 4 (2%) | 8 (4%) | 4 (2%) | 12 (3%) | 8 (2%) | |
With other diseases | 5 (2.5%) | 24 (12%) | 30 (15%) | 25 (12.5%) | 35 (8.7%) | 49 (12.3%) |
Relevance of the Included Studies | Published in 2010 | Published in 2015 | All | ||||
---|---|---|---|---|---|---|---|
China | USA | China | USA | China | USA | p Value | |
Consequence | 0 (0%) | 2 (1%) | 0 (0%) | 5 (2.5%) | 0 (0%) | 7 (1.7%) | 0.015 ** |
Diagnosis | 19 (9.5%) | 15 (7.5%) | 12 (6%) | 16 (8%) | 31 (7.7%) | 31 (7.7%) | 1.000 * |
Disease risk factors | 47 (23.5%) | 29 (14.5%) | 44 (22%) | 30 (15%) | 91 (22.7%) | 59 (14.7%) | 0.005 * |
Epidemiology | 6 (3%) | 9 (4.5%) | 3 (1.5%) | 7 (3.5%) | 9 (2.3%) | 16 (4%) | 0.222 * |
Prevention | 1 (0.5%) | 7 (3.5%) | 2 (1%) | 6 (3%) | 3 (0.7%) | 13 (3.3%) | 0.020 * |
Prognosis | 10 (5%) | 14 (7%) | 14 (7%) | 16 (8%) | 24 (6%) | 30 (7.5%) | 0.481 * |
Treatment | 84 (42%) | 79 (39.5%) | 85 (42.5%) | 70 (35%) | 169 (42.3%) | 149 (37.3%) | 0.170 * |
Multiple | 2 (1%) | 0 (0%) | 3 (1.5%) | 3 (1.5%) | 5 (1.3%) | 3 (0.7%) | 0.725 ** |
Other | 31 (15.5%) | 45 (22.5%) | 37 (18.5%) | 47 (23.5%) | 68 (17%) | 92 (23%) | 0.042 * |
Type of Interventions | Published in 2010 | Published in 2015 | all | ||||
---|---|---|---|---|---|---|---|
China | USA | China | USA | China | USA | p | |
Behavioral or Educational | 0 (0%) | 12 (6.0%) | 1 (0.5%) | 11 (5.5%) | 1 (0.2%) | 23 (5.8%) | 0.000 * |
Biological | 8 (4%) | 5 (2.5%) | 6 (3%) | 7 (3.5%) | 14 (3.5%) | 12 (3%) | 0.842 * |
Diagnostic tests | 10 (5%) | 11 (5.5%) | 12 (6%) | 11 (5.5%) | 22 (5.5%) | 22 (5.5%) | 1.000 * |
Disease management | 8 (4%) | 34 (17%) | 5 (2.5%) | 19 (9.5%) | 13 (3.3%) | 53 (13.3%) | 0.000 * |
Pharmacological | 71 (35.5%) | 41 (20.5%) | 75 (37.5%) | 42 (21%) | 146 (36.5%) | 83 (20.7%) | 0.000 * |
Radiological | 1 (0.5%) | 0 (0%) | 0 (0%) | 0 (0%) | 1 (0.3%) | 0 (0%) | 1.000 ** |
Surgical | 4 (2%) | 10 (5%) | 5 (2.5%) | 3 (1.5%) | 9 (2.3%) | 13 (3.3%) | 0.518 * |
Multiple | 3 (1.5%) | 1 (0.5%) | 0 (0%) | 2 (1%) | 3 (0.7%) | 3 (0.7%) | 1.000 ** |
NA | 95 (47.5%) | 83 (41.5%) | 93 (46.5%) | 101 (50.5%) | 188 (47%) | 184 (46%) | 0.557 * |
Other | 0 (0%) | 3 (1.5%) | 3 (1.5%) | 4 (2%) | 3 (0.7%) | 7 (1.7%) | 0.341 * |
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Fan, H.; Bhurke, S.; Jia, G.; Song, F. Differences and Similarities in Diabetes Research between China and the USA. Int. J. Environ. Res. Public Health 2019, 16, 2989. https://doi.org/10.3390/ijerph16162989
Fan H, Bhurke S, Jia G, Song F. Differences and Similarities in Diabetes Research between China and the USA. International Journal of Environmental Research and Public Health. 2019; 16(16):2989. https://doi.org/10.3390/ijerph16162989
Chicago/Turabian StyleFan, Hong, Sheetal Bhurke, Guizhen Jia, and Fujian Song. 2019. "Differences and Similarities in Diabetes Research between China and the USA" International Journal of Environmental Research and Public Health 16, no. 16: 2989. https://doi.org/10.3390/ijerph16162989