Numerical Simulation of Corneal Fibril Reorientation in Response to External Loading
Abstract
:1. Introduction
2. Methods
2.1. Material Constitutive Model
2.2. Data Analysis
Microstructure Measurements
2.3. Normalisation
2.4. Number of Measurements of Fibril Density at Each Point
2.5. Fibril Reorientation
2.6. Assumptions
2.7. Development of Reorientation Algorithm
2.7.1. Implementation of Fibril Reorientation in Numerical Models
2.7.2. Validation of Reorientation Algorithm
2.8. Further Numerical Assessments
2.8.1. Single Element Model
2.8.2. Full Eye Model
3. Results
3.1. Fibril Reorientation Trends
3.2. Validation of Reorientation Trends against Experimental Measurements
3.3. Finite Element Assessment
3.3.1. Single Element Model
3.3.2. Full Eye Model Application
4. Discussion
Author Contributions
Funding
Acknowledgments
Conflicts of Interest
References
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Zhou, D.; Abass, A.; Eliasy, A.; Movchan, A.; Movchan, N.; Elsheikh, A. Numerical Simulation of Corneal Fibril Reorientation in Response to External Loading. Int. J. Environ. Res. Public Health 2019, 16, 3278. https://doi.org/10.3390/ijerph16183278
Zhou D, Abass A, Eliasy A, Movchan A, Movchan N, Elsheikh A. Numerical Simulation of Corneal Fibril Reorientation in Response to External Loading. International Journal of Environmental Research and Public Health. 2019; 16(18):3278. https://doi.org/10.3390/ijerph16183278
Chicago/Turabian StyleZhou, Dong, Ahmed Abass, Ashkan Eliasy, Alexander Movchan, Natalia Movchan, and Ahmed Elsheikh. 2019. "Numerical Simulation of Corneal Fibril Reorientation in Response to External Loading" International Journal of Environmental Research and Public Health 16, no. 18: 3278. https://doi.org/10.3390/ijerph16183278