Why Does the SARS-CoV-2 Delta VOC Spread So Rapidly? Universal Conditions for the Rapid Spread of Respiratory Viruses, Minimum Viral Loads for Viral Aerosol Generation, Effects of Vaccination on Viral Aerosol Generation, and Viral Aerosol Clouds
Abstract
:1. Viral Load Analysis for Aerosol Generation of Respiratory Viruses and the Original Principle for Viral Aerosol Generation
2. Four Universal Conditions Required for the Rapid Spread of Respiratory Viruses, including SARS-CoV-2 and Its Variants (the Alpha VOC and the Delta VOC), and the Effect of Vaccination on Viral Aerosol Generation
3. Conclusions and Viral Aerosol Clouds
Supplementary Materials
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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Cutoff Particle Diameter to Distinguish Potential Aerosols from Earthbound Respiratory Particles | Minimum Viral Loads Required for Aerosol Generation | |
---|---|---|
Minimum viral loads for aerosol generation (assumptions: homogeneous distribution; virus size 0.09 μm [sphere, dvirus]; one gene copy = a single virion) | 100 μm | ~1.9 × 106 copies mL−1 |
50 μm | ~1.5 × 107 copies mL−1 | |
10 μm | ~1.9 × 109 copies mL−1 | |
5 μm | ~1.5 × 1010 copies mL−1 |
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Lee, B.U. Why Does the SARS-CoV-2 Delta VOC Spread So Rapidly? Universal Conditions for the Rapid Spread of Respiratory Viruses, Minimum Viral Loads for Viral Aerosol Generation, Effects of Vaccination on Viral Aerosol Generation, and Viral Aerosol Clouds. Int. J. Environ. Res. Public Health 2021, 18, 9804. https://doi.org/10.3390/ijerph18189804
Lee BU. Why Does the SARS-CoV-2 Delta VOC Spread So Rapidly? Universal Conditions for the Rapid Spread of Respiratory Viruses, Minimum Viral Loads for Viral Aerosol Generation, Effects of Vaccination on Viral Aerosol Generation, and Viral Aerosol Clouds. International Journal of Environmental Research and Public Health. 2021; 18(18):9804. https://doi.org/10.3390/ijerph18189804
Chicago/Turabian StyleLee, Byung Uk. 2021. "Why Does the SARS-CoV-2 Delta VOC Spread So Rapidly? Universal Conditions for the Rapid Spread of Respiratory Viruses, Minimum Viral Loads for Viral Aerosol Generation, Effects of Vaccination on Viral Aerosol Generation, and Viral Aerosol Clouds" International Journal of Environmental Research and Public Health 18, no. 18: 9804. https://doi.org/10.3390/ijerph18189804