Phenols as a class of molecules have been reported to exhibit higher log maximum fluxes through human stratum corneum, SC, from water, log
JMHAQ, than other classes of molecules. This suggests that their corresponding log maximum fluxes through silicone from water,
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Phenols as a class of molecules have been reported to exhibit higher log maximum fluxes through human stratum corneum, SC, from water, log
JMHAQ, than other classes of molecules. This suggests that their corresponding log maximum fluxes through silicone from water, log
JMPAQ, may be useful to extend the existing
n = 63 log
JMPAQ database to include more log
JMPAQ values greater than 0.0. The log
JMPAQ values for
n = 7 phenols predicted to give log
JMPAQ values greater than 0.0 based on their log
JMHAQ values have been experimentally determined. These
n = 7 new log
JMPAQ values have been added to the existing
n = 63 log
JMPAQ database to give a new
n = 70 database and the
n = 7 literature log
JMHAQ values have been added to the existing
n = 48 log
JMHAQ database (matched to the
n = 63 log
JMPAQ database) to give a new
n = 55 database. The addition of the
n = 7 phenols improved the correlations of these flux databases when fitted to the Roberts-Sloan equation, RS, as well as the correlation between the matched experimental (Exp.) log
JMPAQ with the Exp. log
JMHAQ.
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