Role of FABP5 in T Cell Lipid Metabolism and Function in the Tumor Microenvironment
Abstract
:Simple Summary
Abstract
1. Introduction
2. T Cell Development in the Thymus and Activation in the Periphery
3. External Signals Direct Internal Metabolic Pathways during T Cell Activation
4. Metabolic Programs Determine T Cell Differentiation and Survival
5. Modulation of T Metabolic Programs in the TME
6. Fatty Acid Binding Proteins in T Cells
7. Regulation of T Cell Lipid Metabolism and Function by FABP5
7.1. FABP5 in Naïve T Cells
7.2. FABP5 in Tregs
7.3. FABP5 in Memory T Cells
7.4. FABP5 in Other T Cell Subsets
8. Conclusions and Future Perspectives
Author Contributions
Funding
Conflicts of Interest
References
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Jin, R.; Hao, J.; Yu, J.; Wang, P.; Sauter, E.R.; Li, B. Role of FABP5 in T Cell Lipid Metabolism and Function in the Tumor Microenvironment. Cancers 2023, 15, 657. https://doi.org/10.3390/cancers15030657
Jin R, Hao J, Yu J, Wang P, Sauter ER, Li B. Role of FABP5 in T Cell Lipid Metabolism and Function in the Tumor Microenvironment. Cancers. 2023; 15(3):657. https://doi.org/10.3390/cancers15030657
Chicago/Turabian StyleJin, Rong, Jiaqing Hao, Jianyu Yu, Pingzhang Wang, Edward R. Sauter, and Bing Li. 2023. "Role of FABP5 in T Cell Lipid Metabolism and Function in the Tumor Microenvironment" Cancers 15, no. 3: 657. https://doi.org/10.3390/cancers15030657