Evaluation of Mental Health Factors among People with Systemic Lupus Erythematosus during the SARS-CoV-2 Pandemic
Abstract
:1. Introduction
2. Materials and Methods
Statistical Analysis
3. Results
3.1. Comparison of Coexisting Diseases and Basic Demographic Data between the Group of People with Systemic Lupus Erythematosus and People without a Diagnosis of Systemic Lupus Erythematosus
3.2. Comparison of Mental Health and Sleep Factors between the Group of People with Systemic Lupus Erythematosus and People without a Diagnosis of Systemic Lupus Erythematosus
3.3. Comparison of Mental Health and Sleep Factors after Adjustment for Covariates
4. Discussion
5. Conclusions
Author Contributions
Funding
Conflicts of Interest
References
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Control (n = 589) | SLE (n = 134) | P | ||
---|---|---|---|---|
Sex | female | 275 (46.69) | 119 (88.81) | <0.001 |
male | 314 (53.31) | 15 (11.19) | ||
Age [years], mean ± SD; Me | 39.71 ± 7.07; 39.00 | 38.34 ± 5.62; 38.00 | <0.001 | |
Do you have hypertension? (n, %) | No | 487 (82.68) | 125 (93.28) | 0.003 |
Yes | 102 (17.32) | 9 (6.72) | ||
Do you have diabetes mellitus? (n, %) | No | 574 (97.45) | 133 (99.25) | 0.340 |
Yes | 15 (2.55) | 1 (0.75) | ||
Do you have coronary heart disease? (n, %) | No | 588 (99.83) | 133 (99.25) | 0.814 |
Yes | 1 (0.17) | 1 (0.75) | ||
Are you suffering from heart failure? (n, %) | No | 587 (99.66) | 134 (100.00) | 0.814 |
Yes | 2 (0.34) | 0 (0.00) | ||
Do you have dyslipidemia? (n, %) | No | 470 (79.80) | 115 (85.82) | 0.139 |
Yes | 119 (20.20) | 19 (14.18) | ||
Do you have the chronic obstructive pulmonary disease? (n, %) | No | 586 (99.49) | 134 (100.00) | 0.934 |
Yes | 3 (0.51) | 0 (0.00) | ||
Do you smoke cigarettes? (n, %) | No | 329 (55.86) | 130 (97.01) | <0.001 |
Yes | 260 (44.14) | 4 (2.99) |
Control (n = 589) | SLE (n = 134) | P | ||
---|---|---|---|---|
GAD-7 | Mean ± SD; Me | 6.56±4.06; 6.00 | 19.66±1.10; 20.00 | <0.001 |
≤4 | 216 (36.67) | 0 (0.00) | <0.001 | |
>4 | 373 (63.33) | 134 (100.00) | ||
PHQ-9 | Mean ± SD; Me | 8.65 ± 4.27; 9.00 | 20.61 ± 2.01; 21.00 | <0.001 |
≤ 4 | 137 (23.26) | 0 (0.00) | <0.001 | |
>4 | 452 (76.74) | 134 (100.00) | ||
ISI | Mean ± SD; Me | 10.18 ± 4.96; 11.00 | 22.66 ± 2.30; 23.00 | <0.001 |
≤ 8 | 209 (35.48) | 0 (0.00) | <0.001 | |
>8 | 380 (64.52) | 134 (100.00) |
SLE (No Adjusted) | p | SLE (Adjusted by Potentially Distorting) | p | |||||
---|---|---|---|---|---|---|---|---|
OR | Cl −95% | Cl +95% | OR | Cl −95% | Cl +95% | |||
GAD7 | 3.443 | 2.409 | 4.921 | <0.001 | 3.683 | 2.271 | 5.974 | <0.001 |
PHQ-9 | 4.095 | 2.786 | 6.020 | <0.001 | 4.183 | 2.544 | 6.878 | <0.001 |
ISI | 5.032 | 3.184 | 7.954 | <0.001 | 6.781 | 2.968 | 15.492 | <0.001 |
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Wańkowicz, P.; Szylińska, A.; Rotter, I. Evaluation of Mental Health Factors among People with Systemic Lupus Erythematosus during the SARS-CoV-2 Pandemic. J. Clin. Med. 2020, 9, 2872. https://doi.org/10.3390/jcm9092872
Wańkowicz P, Szylińska A, Rotter I. Evaluation of Mental Health Factors among People with Systemic Lupus Erythematosus during the SARS-CoV-2 Pandemic. Journal of Clinical Medicine. 2020; 9(9):2872. https://doi.org/10.3390/jcm9092872
Chicago/Turabian StyleWańkowicz, Paweł, Aleksandra Szylińska, and Iwona Rotter. 2020. "Evaluation of Mental Health Factors among People with Systemic Lupus Erythematosus during the SARS-CoV-2 Pandemic" Journal of Clinical Medicine 9, no. 9: 2872. https://doi.org/10.3390/jcm9092872