Nanosilver–Silica Composite: Prolonged Antibacterial Effects and Bacterial Interaction Mechanisms for Wound Dressings
Abstract
:1. Introduction
2. Results and Discussion
2.1. Characterization of Ag–SiO2 Composite and SiO2 Particles
2.2. Ag Leaching Profile
2.3. Antibacterial Effects of Ag–SiO2 Composite and Dressings
3. Materials and Methods
3.1. Materials
3.2. Preparation of Ag–SiO2 Composite and SiO2 Particles
3.3. Characterization of Ag–SiO2 Composite and SiO2 Particles
3.4. Ag Leaching from Ag–SiO2 Composite
3.5. Antibacterial Tests
3.5.1. Agar Diffusion Assays
3.5.2. Broth Microdilution Method
3.5.3. Prolonged Antibacterial Effects of Ag–SiO2-G
3.5.4. Mechanisms of Antibacterial Effects of Ag–SiO2 Composite
4. Conclusions
Supplementary Materials
Acknowledgments
Author Contributions
Conflicts of Interest
References
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Materials | SiO2 Particles | Ag Nanoparticles (NPs) of the Composite |
---|---|---|
Median size (nm) | 673 | 5 |
Mean size (nm) | 674 | 5 |
SD (nm) | 22 | 2 |
Minimum particle size (nm) | 616 | 2 |
Maximum particle size (nm) | 724 | 20 |
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Mosselhy, D.A.; Granbohm, H.; Hynönen, U.; Ge, Y.; Palva, A.; Nordström, K.; Hannula, S.-P. Nanosilver–Silica Composite: Prolonged Antibacterial Effects and Bacterial Interaction Mechanisms for Wound Dressings. Nanomaterials 2017, 7, 261. https://doi.org/10.3390/nano7090261
Mosselhy DA, Granbohm H, Hynönen U, Ge Y, Palva A, Nordström K, Hannula S-P. Nanosilver–Silica Composite: Prolonged Antibacterial Effects and Bacterial Interaction Mechanisms for Wound Dressings. Nanomaterials. 2017; 7(9):261. https://doi.org/10.3390/nano7090261
Chicago/Turabian StyleMosselhy, Dina A., Henrika Granbohm, Ulla Hynönen, Yanling Ge, Airi Palva, Katrina Nordström, and Simo-Pekka Hannula. 2017. "Nanosilver–Silica Composite: Prolonged Antibacterial Effects and Bacterial Interaction Mechanisms for Wound Dressings" Nanomaterials 7, no. 9: 261. https://doi.org/10.3390/nano7090261