Differential Pulse Voltammetric Determination of Loperamide in a Pharmaceutical Dosaqe Form
Department of Chemistry, Faculty of Science, Mansoura university, 3451 7 Dumyat, Egypt
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Author to whom correspondence should be addressed.
Sci. Pharm. 2004, 72(3), 239-248; https://doi.org/10.3797/scipharm.aut-04-20
Submission received: 4 May 2004
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Revised: 30 August 2004
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Accepted: 30 August 2004
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Published: 9 September 2004
Abstract
A voltammetric study of the oxidation of loperamide has been carried out at the glassy carbon electrode. This compound exhibited a single peak in Britton-Robinson buffer solutions of pH 5.0–11.0, with a maximum current at pH 8.0. The electrochemical oxidation of loperamide is identified as an irreversible, diffusion-controlled process. Based on this study, a simple, rapid and sensitive voltammetric method was applied, without any interference from the excipients, to the determination of the drug in a capsule dosage form.
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MDPI and ACS Style
Radi, A.; Elmogy, T. Differential Pulse Voltammetric Determination of Loperamide in a Pharmaceutical Dosaqe Form. Sci. Pharm. 2004, 72, 239-248. https://doi.org/10.3797/scipharm.aut-04-20
AMA Style
Radi A, Elmogy T. Differential Pulse Voltammetric Determination of Loperamide in a Pharmaceutical Dosaqe Form. Scientia Pharmaceutica. 2004; 72(3):239-248. https://doi.org/10.3797/scipharm.aut-04-20
Chicago/Turabian StyleRadi, A., and T. Elmogy. 2004. "Differential Pulse Voltammetric Determination of Loperamide in a Pharmaceutical Dosaqe Form" Scientia Pharmaceutica 72, no. 3: 239-248. https://doi.org/10.3797/scipharm.aut-04-20
