Plants, Volume 13, Issue 2 (January-2 2024) – 182 articles
Research on Centaurea cineraria L. subsp. cineraria revealed that this endemic plant from Italy provides extracts with inhibitory activity on the radicle growth of broomrapes (parasitic weeds from Phelipanche ramosa, Orobanche minor, Orobanche crenata, and Orobanche cumana). The purification of the most active extract gave some active sesquiterpene lactones, namely isocnicin, cnicin, and salonitenolide. Structure–activity relationships emphasized the significance of α,β-unsaturated lactone rings. The acetylation of salonitenolide produced a significantly more active derivative, attributed to distinct lipophilicity and the absence of H-bond donors. The potential of C. cineraria in managing parasitic weeds and developing herbicides based on natural products was then revealed. View this paper
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