The Long-Term Mortality Effects Associated with Exposure to Particles and NOx in the Malmö Diet and Cancer Cohort
Abstract
:1. Introduction
2. Materials and Methods
2.1. Description of the Study Population and the Study Period
2.2. Air Pollution Exposure Assessment
2.3. Outcome Assessment
2.4. Covariates
2.5. Statistical Analysis
3. Results
3.1. Hazard Ratios Associated with Exposure
3.2. Sensitivity Analysis
4. Discussion
4.1. Key Results
4.2. The Calculated Hazard Ratios and Possible Explanations
4.3. NOx as an Indicator for Other Harmful Exposures
4.4. Strengths and Limitations of This Study
4.5. Future Research Needs and Policy Implications
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
Appendix A
Air Pollutant * | Model † | IQR (µg m−3) | HR | 95% CI | p-Value |
---|---|---|---|---|---|
PM10 | M1 | 2.7 | 1.05 | 1.02–1.07 | <0.001 |
M2 | - | 1.02 | 0.99–1.05 | 0.14 | |
M3 | - | 1.01 | 0.98–1.04 | 0.43 | |
PM2.5 | M1 | 1.6 | 1.01 | 0.99–1.03 | 0.43 |
M2 | - | 1.00 | 0.98–1.02 | 0.99 | |
M3 | - | 1.00 | 0.98–1.02 | 0.77 | |
BC | M1 | 0.15 | 1.13 | 1.09–1.16 | <0.001 |
M2 | - | 1.06 | 1.03–1.09 | <0.001 | |
M3 | - | 1.05 | 1.02–1.08 | 0.004 | |
NOx | M1 | 9.7 | 1.15 | 1.12–1.19 | <0.001 |
M2 | - | 1.08 | 1.05–1.12 | <0.001 | |
M3 | - | 1.08 | 1.05–1.12 | <0.001 | |
PM10 + BC | M1 | - | 1.00 | 0.97–1.03 | 0.76 |
M2 | - | 1.00 | 0.97–1.03 | 0.82 | |
M3 | - | 0.99 | 0.96–1.02 | 0.49 | |
BC + PM10 | M1 | - | 1.13 | 1.09–1.17 | <0.001 |
M2 | - | 1.06 | 1.02–1.10 | 0.001 | |
M3 | - | 1.06 | 1.02–1.10 | 0.004 | |
PM10 + NOx | M1 | - | 0.99 | 0.96–1.02 | 0.49 |
M2 | - | 0.99 | 0.96–1.02 | 0.42 | |
M3 | - | 0.98 | 0.95–1.01 | 0.16 | |
NOx + PM10 | M1 | - | 1.16 | 1.12–1.20 | <0.001 |
M2 | - | 1.09 | 1.05–1.13 | <0.001 | |
M3 | - | 1.10 | 1.06–1.14 | <0.001 | |
PM2.5 + BC | M1 | - | 0.99 | 0.98–1.01 | 0.52 |
M2 | - | 0.99 | 0.97–1.01 | 0.53 | |
M3 | - | 0.99 | 0.97–1.01 | 0.41 | |
BC + PM2.5 | M1 | - | 1.13 | 1.09–1.16 | <0.001 |
M2 | - | 1.06 | 1.03–1.09 | <0.001 | |
M3 | - | 1.05 | 1.02–1.09 | 0.003 | |
PM2.5 + NOx | M1 | - | 0.99 | 0.97–1.01 | 0.32 |
M2 | - | 0.99 | 0.97–1.01 | 0.34 | |
M3 | - | 0.99 | 0.97–1.01 | 0.24 | |
NOx + PM2.5 | M1 | - | 1.16 | 1.12–1.19 | <0.001 |
M2 | - | 1.09 | 1.05–1.13 | <0.001 | |
M3 | - | 1.09 | 1.05–1.12 | <0.001 | |
BC + NOx | M1 | - | 0.99 | 0.93–1.05 | 0.67 |
M2 | - | 0.94 | 0.88–1.01 | 0.08 | |
M3 | - | 0.92 | 0.86–0.98 | 0.02 | |
NOx + BC | M1 | - | 1.17 | 1.09–1.25 | <0.001 |
M2 | - | 1.15 | 1.07–1.23 | <0.001 | |
M3 | - | 1.17 | 1.09–1.26 | <0.001 |
Air Pollutant * | Model † | IQR (µg m−3) | HR | 95% CI | p-Value |
---|---|---|---|---|---|
PM10 | M1 | 2.1 | 1.16 | 1.12–1.21 | <0.001 |
M2 | - | 1.08 | 1.03–1.12 | <0.001 | |
M3 | - | 1.06 | 1.02–1.11 | 0.007 | |
PM2.5 | M1 | 1.7 | 1.11 | 1.05–1.17 | <0.001 |
M2 | - | 1.04 | 0.98–1.10 | 0.24 | |
M3 | - | 1.01 | 0.95–1.08 | 0.69 | |
BC | M1 | 0.14 | 1.15 | 1.11–1.18 | <0.001 |
M2 | - | 1.08 | 1.04–1.11 | <0.001 | |
M3 | - | 1.07 | 1.04–1.11 | <0.001 | |
NOx | M1 | 11.4 | 1.19 | 1.15–1.22 | <0.001 |
M2 | - | 1.11 | 1.07–1.15 | <0.001 | |
M3 | - | 1.11 | 1.07–1.16 | <0.001 | |
PM10 + NOx | M1 | - | 0.98 | 0.92–1.04 | 0.49 |
M2 | - | 0.95 | 0.89–1.01 | 0.10 | |
M3 | - | 0.90 | 0.84–0.97 | 0.004 | |
NOx + PM10 | M1 | - | 1.20 | 1.14–1.27 | <0.001 |
M2 | - | 1.15 | 1.09–1.22 | <0.001 | |
M3 | - | 1.19 | 1.13–1.26 | <0.001 | |
PM2.5 + BC | M1 | - | 0.94 | 0.88–1.00 | 0.07 |
M2 | - | 0.94 | 0.87–1.01 | 0.09 | |
M3 | - | 0.92 | 0.85–0.99 | 0.02 | |
BC + PM2.5 | M1 | - | 1.17 | 1.13–1.21 | <0.001 |
M2 | - | 1.10 | 1.06–1.14 | <0.001 | |
M3 | - | 1.10 | 1.06–1.14 | <0.001 | |
PM2.5 + NOx | M1 | - | 0.96 | 0.90–1.02 | 0.22 |
M2 | - | 0.95 | 0.88–1.01 | 0.11 | |
M3 | - | 0.92 | 0.85–0.98 | 0.01 | |
NOx + PM2.5 | M1 | - | 1.20 | 1.15–1.24 | <0.001 |
M2 | - | 1.13 | 1.08–1.17 | <0.001 | |
M3 | - | 1.14 | 1.10–1.19 | <0.001 | |
BC + NOx | M1 | - | 1.02 | 0.97–1.09 | 0.41 |
M2 | - | 0.98 | 0.93–1.05 | 0.61 | |
M3 | - | 0.95 | 0.89–1.01 | 0.10 | |
NOx + BC | M1 | - | 1.16 | 1.09–1.23 | <0.001 |
M2 | - | 1.13 | 1.05–1.21 | <0.001 | |
M3 | - | 1.17 | 1.09–1.26 | <0.001 |
Air Pollutant * | Model † | IQR (µg m−3) | HR | 95% CI | p-Value |
---|---|---|---|---|---|
PM10 | M1 | 2.3 | 1.17 | 1.12–1.23 | <0.001 |
M2 | - | 1.09 | 1.04–1.14 | <0.001 | |
M3 | - | 1.08 | 1.03–1.13 | 0.002 | |
PM2.5 | M1 | 1.5 | 1.18 | 1.11–1.26 | <0.001 |
M2 | - | 1.10 | 1.03–1.17 | 0.002 | |
M3 | - | 1.09 | 1.02–1.17 | 0.009 | |
BC | M1 | 0.15 | 1.14 | 1.11–1.18 | <0.001 |
M2 | - | 1.07 | 1.03–1.10 | <0.001 | |
M3 | - | 1.06 | 1.02–1.10 | 0.002 | |
NOx | M1 | 12.7 | 1.16 | 1.12–1.19 | <0.001 |
M2 | - | 1.08 | 1.05–1.12 | <0.001 | |
M3 | - | 1.08 | 1.05–1.12 | <0.001 | |
PM10 + NOx | M1 | - | 1.03 | 0.96–1.10 | 0.42 |
M2 | - | 1.00 | 0.93–1.08 | 0.94 | |
M3 | - | 0.99 | 0.92–1.06 | 0.74 | |
NOx + PM10 | M1 | - | 1.14 | 1.08–1.20 | <0.001 |
M2 | - | 1.08 | 1.03–1.14 | 0.004 | |
M3 | - | 1.09 | 1.03–1.16 | 0.002 | |
PM2.5 + BC | M1 | - | 1.03 | 0.96–1.11 | 0.41 |
M2 | - | 1.04 | 0.96–1.13 | 0.30 | |
M3 | - | 1.04 | 0.96–1.13 | 0.36 | |
BC + PM2.5 | M1 | - | 1.13 | 1.08–1.18 | <0.001 |
M2 | - | 1.05 | 1.01–1.10 | 0.02 | |
M3 | - | 1.05 | 1.00–1.09 | 0.05 | |
PM2.5 + NOx | M1 | - | 1.05 | 0.98–1.13 | 0.13 |
M2 | - | 1.04 | 0.97–1.11 | 0.31 | |
M3 | - | 1.02 | 0.95–1.10 | 0.53 | |
NOx + PM2.5 | M1 | - | 1.14 | 1.10–1.18 | <0.001 |
M2 | - | 1.07 | 1.03–1.12 | <0.001 | |
M3 | - | 1.08 | 1.04–1.12 | <0.001 | |
BC + NOx | M1 | - | 1.03 | 0.97–1.10 | 0.38 |
M2 | - | 0.99 | 0.92–1.05 | 0.67 | |
M3 | - | 0.96 | 0.89–1.03 | 0.23 | |
NOx + BC | M1 | - | 1.13 | 1.06–1.20 | <0.001 |
M2 | - | 1.10 | 1.03–1.17 | 0.006 | |
M3 | - | 1.12 | 1.05–1.20 | 0.001 |
Air Pollutant | Age Group | HR | 95% CI | p-Value |
---|---|---|---|---|
PM10 | Group 1 ≤ 50 years | 1.00 | 0.84–1.19 | 0.99 |
50 years < Group 2 ≤ 55 years | 1.08 | 0.95–1.23 | 0.23 | |
55 years < Group 3 ≤ 60 years | 1.02 | 0.91–1.14 | 0.72 | |
60 years < Group 4 ≤ 65 years | 1.10 | 1.02–1.20 | 0.02 | |
65 years < Group 5 ≤ 70 years | 1.12 | 1.01–1.23 | 0.03 | |
Group 6 > 70 years | 1.02 | 0.91–1.15 | 0.73 | |
PM2.5 | Group 1 ≤ 50 years | 1.06 | 0.82–1.37 | 0.65 |
50 years < Group 2 ≤ 55 years | 1.05 | 0.86–1.28 | 0.61 | |
55 years < Group 3 ≤ 60 years | 0.92 | 0.78–1.08 | 0.31 | |
60 years < Group 4 ≤ 65 years | 1.06 | 0.94–1.20 | 0.37 | |
65 years < Group 5 ≤ 70 years | 1.16 | 1.00–1.34 | 0.05 | |
Group 6 > 70 years | 0.94 | 0.77–1.15 | 0.56 | |
BC | Group 1 ≤ 50 years | 1.04 | 0.92–1.18 | 0.54 |
50 years < Group 2 ≤ 55 years | 1.07 | 0.98–1.18 | 0.14 | |
55 years < Group 3 ≤ 60 years | 1.05 | 0.96–1.14 | 0.28 | |
60 years < Group 4 ≤ 65 years | 1.10 | 1.03–1.17 | 0.004 | |
65 years < Group 5 ≤ 70 years | 1.09 | 1.01–1.17 | 0.02 | |
Group 6 > 70 years | 1.01 | 0.93–1.10 | 0.80 | |
NOx | Group 1 ≤ 50 years | 1.05 | 0.90–1.23 | 0.52 |
50 years < Group 2 ≤ 55 years | 1.11 | 1.01–1.23 | 0.04 | |
55 years < Group 3 ≤ 60 years | 1.07 | 0.97–1.17 | 0.16 | |
60 years < Group 4 ≤ 65 years | 1.12 | 1.05–1.20 | 0.001 | |
65 years < Group 5 ≤ 70 years | 1.11 | 1.03–1.20 | 0.006 | |
Group 6 > 70 years | 1.05 | 0.95–1.15 | 0.35 |
Air Pollutant | Age Group | HR | 95% CI | p-Value |
---|---|---|---|---|
PM10 + NOx | Group 1 ≤ 50 years | 0.89 | 0.67–1.17 | 0.41 |
50 years < Group 2 ≤ 55 years | 0.91 | 0.73–1.14 | 0.43 | |
55 years < Group 3 ≤ 60 years | 0.88 | 0.73–1.07 | 0.20 | |
60 years < Group 4 ≤ 65 years | 0.97 | 0.84–1.12 | 0.69 | |
65 years < Group 5 ≤ 70 years | 1.00 | 0.84–1.18 | 0.99 | |
Group 6 > 70 years | 0.88 | 0.69–1.13 | 0.32 | |
NOx + PM10 | Group 1 ≤ 50 years | 1.14 | 0.89–1.45 | 0.29 |
50 years < Group 2 ≤ 55 years | 1.18 | 0.99–1.40 | 0.06 | |
55 years < Group 3 ≤ 60 years | 1.16 | 0.99–1.36 | 0.06 | |
60 years < Group 4 ≤ 65 years | 1.14 | 1.02–1.29 | 0.03 | |
65 years < Group 5 ≤ 70 years | 1.12 | 0.98–1.28 | 0.11 | |
Group 6 > 70 years | 1.14 | 0.94–1.39 | 0.18 | |
PM2.5 + BC | Group 1 ≤ 50 years | 1.02 | 0.74–1.40 | 0.91 |
50 years < Group 2 ≤ 55 years | 0.94 | 0.74–1.20 | 0.63 | |
55 years < Group 3 ≤ 60 years | 0.81 | 0.67–1.00 | 0.05 | |
60 years < Group 4 ≤ 65 years | 0.94 | 0.81–1.09 | 0.40 | |
65 years < Group 5 ≤ 70 years | 1.08 | 0.90–1.29 | 0.40 | |
Group 6 > 70 years | 0.86 | 0.65–1.14 | 0.29 | |
BC + PM2.5 | Group 1 ≤ 50 years | 1.04 | 0.88–1.21 | 0.67 |
50 years < Group 2 ≤ 55 years | 1.09 | 0.97–1.23 | 0.15 | |
55 years < Group 3 ≤ 60 years | 1.11 | 1.00–1.23 | 0.04 | |
60 years < Group 4 ≤ 65 years | 1.12 | 1.03–1.20 | 0.004 | |
65 years < Group 5 ≤ 70 years | 1.06 | 0.98–1.16 | 0.16 | |
Group 6 > 70 years | 1.05 | 0.94–1.18 | 0.36 | |
PM2.5 + NOx | Group 1 ≤ 50 years | 1.02 | 0.76–1.37 | 0.87 |
50 years < Group 2 ≤ 55 years | 0.93 | 0.74–1.17 | 0.54 | |
55 years < Group 3 ≤ 60 years | 0.83 | 0.69–1.00 | 0.06 | |
60 years < Group 4 ≤ 65 years | 0.95 | 0.83–1.10 | 0.51 | |
65 years < Group 5 ≤ 70 years | 1.07 | 0.90–1.26 | 0.44 | |
Group 6 > 70 years | 0.82 | 0.63–1.06 | 0.13 | |
NOx + PM2.5 | Group 1 ≤ 50 years | 1.04 | 0.88–1.24 | 0.63 |
50 years < Group 2 ≤ 55 years | 1.13 | 1.01–1.27 | 0.04 | |
55 years < Group 3 ≤ 60 years | 1.12 | 1.01–1.25 | 0.03 | |
60 years < Group 4 ≤ 65 years | 1.14 | 1.05–1.23 | 0.002 | |
65 years < Group 5 ≤ 70 years | 1.10 | 1.00–1.20 | 0.04 | |
Group 6 > 70 years | 1.11 | 0.98–1.25 | 0.09 | |
BC + NOx | Group 1 ≤ 50 years | 1.01 | 0.78–1.32 | 0.92 |
50 years < Group 2 ≤ 55 years | 0.95 | 0.79–1.14 | 0.56 | |
55 years < Group 3 ≤ 60 years | 0.98 | 0.84–1.15 | 0.84 | |
60 years < Group 4 ≤ 65 years | 1.02 | 0.90–1.15 | 0.80 | |
65 years < Group 5 ≤ 70 years | 0.99 | 0.86–1.14 | 0.88 | |
Group 6 > 70 years | 0.87 | 0.72–1.05 | 0.15 | |
NOx + BC | Group 1 ≤ 50 years | 1.04 | 0.76–1.42 | 0.82 |
50 years < Group 2 ≤ 55 years | 1.17 | 0.96–1.43 | 0.12 | |
55 years < Group 3 ≤ 60 years | 1.09 | 0.91–1.30 | 0.37 | |
60 years < Group 4 ≤ 65 years | 1.10 | 0.96–1.27 | 0.16 | |
65 years < Group 5 ≤ 70 years | 1.13 | 0.96–1.32 | 0.13 | |
Group 6 > 70 years | 1.21 | 0.97–1.50 | 0.09 |
Air Pollutant | Survival Time | HR | 95% CI | p-Value |
---|---|---|---|---|
PM10 | 0–10 years | 1.11 | 1.02–1.20 | 0.01 |
>10 years | 1.06 | 1.01–1.12 | 0.02 | |
PM2.5 | 0–10 years | 1.16 | 1.00–1.35 | 0.05 |
>10 years | 1.01 | 0.94–1.08 | 0.76 | |
BC | 0–10 years | 1.10 | 1.03–1.18 | 0.003 |
>10 years | 1.06 | 1.02–1.10 | 0.001 | |
NOx | 0–10 years | 1.09 | 1.03–1.14 | 0.001 |
>10 years | 1.12 | 1.06–1.18 | <0.001 |
Air Pollutant | Survival Time | HR | 95% CI | p-Value |
---|---|---|---|---|
PM10 + NOx | 0–10 years | 1.00 | 0.88–1.14 | 0.95 |
>10 years | 0.92 | 0.83–1.01 | 0.07 | |
NOx + PM10 | 0–10 years | 1.08 | 1.00–1.17 | 0.05 |
>10 years | 1.20 | 1.09–1.33 | <0.001 | |
PM2.5 + BC | 0–10 years | 1.02 | 0.85–1.23 | 0.82 |
>10 years | 0.93 | 0.86–1.01 | 0.10 | |
BC + PM2.5 | 0–10 years | 1.10 | 1.01–1.19 | 0.03 |
>10 years | 1.08 | 1.04–1.13 | <0.001 | |
PM2.5 + NOx | 0–10 years | 1.05 | 0.89–1.24 | 0.54 |
>10 years | 0.92 | 0.85–1.00 | 0.04 | |
NOx + PM2.5 | 0–10 years | 1.08 | 1.02–1.14 | 0.01 |
>10 years | 1.15 | 1.08–1.23 | <0.001 | |
BC + NOx | 0–10 years | 1.03 | 0.91–1.16 | 0.62 |
>10 years | 0.91 | 0.81–1.01 | 0.09 | |
NOx + BC | 0–10 years | 1.07 | 0.97–1.17 | 0.18 |
>10 years | 1.27 | 1.08–1.49 | 0.003 |
PM10 lag0 | PM2.5 lag0 | BC lag0 | NOx lag0 | |
---|---|---|---|---|
PM10 lag0 | 1 | |||
PM2.5 lag0 | 0.81 | 1 | ||
BC lag0 | 0.55 | 0.25 | 1 | |
NOx lag0 | 0.24 | 0.03 | 0.50 | 1 |
PM10 lag1–5 | PM2.5 lag1–5 | BC lag1–5 | NOx lag1–5 | |
PM10 lag1–5 | 1 | |||
PM2.5 lag1–5 | 0.81 | 1 | ||
BC lag1–5 | 0.85 | 0.64 | 1 | |
NOx lag1–5 | 0.19 | −0.18 | 0.41 | 1 |
PM10 lag6–10 | PM2.5 lag6–10 | BC lag6–10 | NOx lag6–10 | |
PM10 lag6–10 | 1 | |||
PM2.5 lag6–10 | 0.90 | 1 | ||
BC lag6–10 | 0.84 | 0.66 | 1 | |
NOx lag6–10 | 0.22 | −0.09 | 0.47 | 1 |
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Air Pollutant | Number of Obs. | Mean | SD | Median | 25 Percentile | 75 Percentile | Min. | Max. |
---|---|---|---|---|---|---|---|---|
PM10 lag0 | 552,608 | 15.9 | 2.2 | 15.7 | 14.5 | 17.2 | 9.7 | 27.6 |
PM2.5 lag0 | 552,608 | 10.9 | 1.8 | 10.8 | 9.8 | 11.4 | 6.6 | 18.4 |
BC lag0 | 552,608 | 1.0 | 0.1 | 1.0 | 0.9 | 1.1 | 0.7 | 1.9 |
NOx lag0 | 552,608 | 26.5 | 8.8 | 24.9 | 20.8 | 30.5 | 6.8 | 130.0 |
Air pollutant | Number of obs. | Mean | SD | Median | 25 percentile | 75 percentile | Min. | Max. |
PM10 lag1–5 | 534,059 | 15.8 | 1.5 | 15.9 | 14.8 | 16.9 | 11.2 | 25.8 |
PM2.5 lag1–5 | 534,059 | 10.9 | 0.9 | 10.8 | 10.1 | 11.8 | 8.8 | 14.9 |
BC lag1–5 | 534,059 | 0.9 | 0.1 | 1.0 | 0.9 | 1.0 | 0.7 | 1.7 |
NOx lag1–5 | 534,059 | 28.3 | 10.0 | 26.3 | 21.7 | 33.0 | 7.8 | 134.0 |
Air pollutant | Number of obs. | Mean | SD | Median | 25 percentile | 75 percentile | Min. | Max. |
PM10 lag6–10 | 417,278 | 15.6 | 1.6 | 15.6 | 14.5 | 16.8 | 11.2 | 24.6 |
PM2.5 lag6–10 | 417,278 | 10.7 | 0.9 | 10.6 | 10.0 | 11.5 | 8.8 | 13.8 |
BC lag6–10 | 417,278 | 0.9 | 0.1 | 0.9 | 0.9 | 1.0 | 0.7 | 1.7 |
NOx lag6–10 | 417,278 | 30.1 | 10.6 | 28.1 | 22.7 | 35.4 | 8.6 | 134.0 |
Covariate | Number of Obs. | Mean | SD | Min. | Max. |
---|---|---|---|---|---|
Age at enrollment | 30,438 | 58.0 | 7.6 | 44.5 | 73.6 |
Systolic blood pressure | 30,389 | 141.1 | 20.1 | 61 | 240 |
Diastolic blood pressure | 30,386 | 85.6 | 10.0 | 40 | 150 |
Waist/Hip ratio | 30,362 | 0.85 | 0.1 | 0.4 | 1.9 |
Alcohol consumption (g day−1) | 28,228 | 10.7 | 12.7 | 0 | 194 |
Covariate | Number of Obs. | Category 1 | Category 2 | Category 3 |
---|---|---|---|---|
Gender | 30,438 | Male (39.8%) | Female (60.2%) | - |
Smoking status | 28,557 | Never smoker (37.9%) | Former smoker (33.8%) | Current smoker (28.3%) |
Educational level | 28,492 | Elementary school (42.0%) | High school (35.0%) | College (23.0%) |
Cohabitation | 28,554 | Yes (75.4%) | No (24.6%) | - |
Physical activity | 30,164 | Low (33.1%) | Medium (33.3%) | High (33.5%) |
Antihypertensive drugs | 28,446 | Yes (17.8%) | No (82.2%) | - |
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Olstrup, H.; Flanagan, E.; Persson, J.-O.; Rittner, R.; Krage Carlsen, H.; Stockfelt, L.; Xu, Y.; Rylander, L.; Gustafsson, S.; Spanne, M.; et al. The Long-Term Mortality Effects Associated with Exposure to Particles and NOx in the Malmö Diet and Cancer Cohort. Toxics 2023, 11, 913. https://doi.org/10.3390/toxics11110913
Olstrup H, Flanagan E, Persson J-O, Rittner R, Krage Carlsen H, Stockfelt L, Xu Y, Rylander L, Gustafsson S, Spanne M, et al. The Long-Term Mortality Effects Associated with Exposure to Particles and NOx in the Malmö Diet and Cancer Cohort. Toxics. 2023; 11(11):913. https://doi.org/10.3390/toxics11110913
Chicago/Turabian StyleOlstrup, Henrik, Erin Flanagan, Jan-Olov Persson, Ralf Rittner, Hanne Krage Carlsen, Leo Stockfelt, Yiyi Xu, Lars Rylander, Susanna Gustafsson, Mårten Spanne, and et al. 2023. "The Long-Term Mortality Effects Associated with Exposure to Particles and NOx in the Malmö Diet and Cancer Cohort" Toxics 11, no. 11: 913. https://doi.org/10.3390/toxics11110913