Table of Contents
Non-Coding RNA, Volume 4, Issue 1 (March 2018)
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Cover Story (view full-size image) The nuclear RNA exosome regulates the metabolism of a huge plethora of RNA species. Recent studies [...] Read more. The nuclear RNA exosome regulates the metabolism of a huge plethora of RNA species. Recent studies have identified a number of co-factors that direct the exosome towards specific substrates. Moreover, in addition to its role in regulating the activity and maintaining the fidelity of gene expression, its physiological significance in multiple biological processes—such as DNA damage response, R-loop resolution, RNA export, translation, cell differentiation and virus infectivity—is gradually being understood. View this paper