Novel Insights into Liver Metabolism

Dear Colleagues,

Thousands of diverse chemical reactions take place in the liver. Its metabolic role is directly related to the biological processes concerning proteins, lipids, carbohydrates, drugs and toxins. Each reaction might be interrupted by molecular or functional disturbances, which will finally result in the development of hepatic failure. Thus, there is an urgent need to explore new diagnostic and therapeutic strategies that can become more specific and more effective to improve liver metabolism. This Special Issue will gather publications exploring the phenomenon of liver metabolism from various perspectives. Both original articles and  reviews are welcomed.

Potential topics include but are not limited to the following:

• New biomarkers of acute liver failure, liver steatosis and fibrosis;
• Novel parameters of hepatic decompensation in the course of chronic liver disorders;
• A comparison between imaging studies and advanced laboratory tests in the evaluation of the liver function;
• New agents and medical approaches possibly used in cirrhotic patients to improve the function/metabolism of the liver;
• Relationships between liver metabolism and other systemic failures due to biochemical processes;
• The role of miRNAs and other biological particles implied in the natural history of liver failure;
• Possible novel pathways in the diagnosis and treatment of autoimmune liver diseases;
• Relationships between impaired liver metabolism and the risk of its cancer;
• In vitro and in vivo models for studying oxidative stress in the liver;
• The involvement of microbiota in the impaired liver metabolism.

Dr. Agata Michalak
Prof. Dr. Halina Cichoż-Lach
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biomedicines is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• liver
• metabolism
• oxidative stress
• mi-RNAs
• cirrhosis
• alcohol-related liver disease
• autoimmune liver disorders
• hepatocellular cancer
• liver steatosis
• microbiota
• diagnostic markers