The Effect of Cancer Chemotherapy on the Gut Microbiota

Dear Colleagues,

The complex interplay between cancer chemotherapy, the immune system and the gut microbiome has garnered substantial scientific interest. As a core component of cancer treatment, chemotherapy profoundly alters the gut microbiota. These changes can impact immune system function, affecting patients' cardiometabolic health and susceptibility to infection. The disrupted microbiome may also be key to understanding side effects and late effects of chemotherapy such as dyslipidemia and premature ageing. This Special Issue aims to elucidate these interactions, focusing on chemotherapy-induced changes to the gut microbiome and the resultant effects. We welcome contributions that shed light on the mechanistic processes, clinical outcomes and potential strategies to modify or adapt the gut microbiota post-chemotherapy. By compiling research and reviews, this issue seeks to provide a comprehensive perspective, promoting improved patient care in oncology through an integrated understanding of the chemotherapy–microbiome–immunity axis.

Dr. Abderrahim Benmoussa
Guest Editor

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• cancer
• chemotherapy
• immune system
• gut microbiome
• cardiometabolic disorders
• infections
• side-effects
• late effects
• clinical outcomes
• oncology