Understanding Cancer’s Inflammatory Crosstalk: The Potential for Precision Targeting

Dear Colleagues,

The complex and heterogeneous nature of cancer is governed by dysregulated signaling networks, which determine cellular processes like proliferation, survival, angiogenesis and metastasis. Inflammation represents a key component of the tumor microenvironment and has been linked to tumorigenesis. Moreover, the complex interplay between inflammation and cancer signaling pathways presents itself with an immense potential for developing targeted therapeutics. A deep understanding of this crosstalk will direct the current research towards developing novel and effective strategies for modulating the tumor microenvironment, along with enhanced immune response and minimal effect on normal cells. This Special Issue of Biomedicines focuses on highlighting the current knowledge and research trends in understanding, identifying and targeting cancer signaling pathways for implementing precision therapies, with special emphasis on the inflammation – cancer interplay.

We cordially invite investigators to submit original research or review articles pertaining to (but not limited to) inflammatory mediators in cancer development and progression,  anti-tumor immunity, inflammatory signaling pathways in cancer, tumor microenvironment, cell death pathways, immune checkpoint blockade, inflammation mediated immune evasion, metastasis and therapy resistance.

Dr. Sabira Mohammed
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biomedicines is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• inflammatory pathways
• signal transduction
• targeted therapy
• precision oncology
• tumor biology
• cell death
• molecular targets
• cancer resistance
• inhibitors
• tumor microenvironment
• metastasis