Mechanisms and Novel Therapeutic Approaches for Colorectal Cancer

Dear Colleagues,

Since the 1970s, the molecular biological and biochemical mechanisms of the pathogenesis of colon adenocarcinomas have been studied to provide a better understanding of colorectal cancer. Many studies have been particularly valuable in understanding and elucidating the mechanisms involved in the development of malignancy in detail. Although several genetic factors involved in the initiation, promotion, progression, and metastasis of colorectal cancer have recently been well established, the field of colorectal cancer treatment still has several unmet medical needs. Nevertheless, various academic fields have been advanced, along with the development of state-of-the-art technologies, and such areas have contributed greatly to our understanding of colorectal cancer. This has also enabled early detection of precancerous lesions and expanded appropriate diagnosis so as to make possible the further development of effective treatments. At this point, we recognize the need to organize information from the past and a common understanding of emerging technologies. This Special Issue will consider various treatment options in non-clinical fields based on information on the mechanism, pathogenesis, diagnosis, and prognosis of colorectal cancer.

Dr. Keun-Yeong Jeong
Guest Editor

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• colorectal cancer
• anticancer drugs
• chemotherapy
• radiotherapy
• target therapy
• immunotherapy
• microbiome
• drug resistance
• non-clinical study