Autonomic Dysfunction in Neurological Disorders: Novel Mechanisms and Targets

Dear Colleagues,

The dysfunction of the autonomic nervous system is associated with many neurological diseases as a consequence or causality of primary diseases. Studies have been carried out to determine the mechanisms of dysautonomia in neurological disorders such as Alzheimer’s disease, Parkinson’s disease, depression, and neurogenic hypertension. In addition, dysautonomia also importantly contributes to metabolic diseases, such as diabetes, obesity, and metabolic syndrome, because it may lead to insulin resistance, altered lipid metabolism, and hypertension in metabolic syndrome. In a certain sensorium, autonomic dysfunction is associated with multiple diseases (e.g., diabetes mellitus and depression), suggesting that autonomic dysfunction is possibly a common mechanism that governs their pathological process. However, the role of autonomic dysfunction in creating or maintaining the pathology of neurological diseases is not still completely understood. Recovering altered autonomic function provides a potential therapy that can be used to treat certain neurological diseases. This Special Issue invites investigators to contribute original research articles and review articles that will help us understand the novel mechanisms of autonomic dysfunction in neurological diseases. Potential topics include, but are not limited to, the following: autonomic dysfunction in neurological disorders (such as Alzheimer's disease, Parkinson's disease, and depression); dysautonomia in insulin resistance in metabolic diseases; and dysautonomia in response to external environmental changes (such as stress, traumatic brain injury, or hormonal imbalances).

Dr. De-Pei Li
Prof. Dr. Zixi Cheng
Guest Editors

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