New Perspectives on Chronic Kidney Disease

Dear Colleagues,

The kidney is a vital organ in the human body, responsible for filtering waste products and excess fluids from the blood, producing urine as a result. Located on either side of the spine in the retroperitoneum, the kidneys also play a crucial role in regulating electrolyte levels, blood pressure, and the production of red blood cells. Each kidney contains around one million nephrons, the functional units responsible for filtration. Each nephron includes a renal corpuscle and a renal tubule, with segments such as the proximal convoluted tubule, loop of Henle, distal convoluted tubule, and connecting tubule.

Chronic kidney disease is a progressive condition that affects more than 10% of the general population worldwide. Early detection plays a critical role in preventing the onset of kidney failure. Physicians assess patients for indicators of renal disease and perform a range of diagnostic tests to evaluate kidney function, including measurements such as serum creatinine level, cystatin C, blood urea nitrogen, glomerular filtration rate (eGFR), electrolyte levels, and red blood cell count, as well as urinalysis. On occasion, a biopsy of kidney tissue may be required for accurate diagnosis. To date, these tests have represented the standards for the diagnostics of kidney diseases. However, new technologies offer promising new ways to diagnose and prognose kidney diseases. Biomarkers other than plasma creatinine and the glomerular filtration rate are becoming crucial for the diagnosis and assessment of a patient’s condition. New diagnostic methods play a significant role in diagnosis and provide greater treatment options.

The aim of this Special Issue is to present recent advances in chronic kidney disease.

Both original research articles and reviews from the entire nephrology community are welcome.

Dr. Ewelina Młynarska
Guest Editor

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• chronic kidney disease
• SGLT2 inhibitors
• diabetic kidney disease
• acute kidney injury
• hemodialysis
• electrolytes
• biopsy
• nephron