Intrinsic Metabolic Factors in Non-small Cell Lung Cancer

A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Cancer Biology and Oncology".

Deadline for manuscript submissions: 15 July 2024 | Viewed by 159

Special Issue Editor


E-Mail Website
Guest Editor
Department of Medicine, Royal College of Surgeons in Ireland, D02 YN77 Dublin, Ireland
Interests: metabolism; non-small cell lung cancer; immunotherapy; KRAS; LKB1

Special Issue Information

Dear Colleagues,

Non-small cell lung cancer accounts for 85% of all cases of lung cancer and is characterized by high glucose and lactate use, and high heterogeneity in their metabolic pathways. Metabolic reprogramming is a hallmark of cancer which contributes to essential processes required for cell survival, growth, and proliferation. Recent advances in biochemical and molecular biological tools have reignited the metabolic field and offered an unprecedented opportunity to unravel and delineate many aspects of cancer metabolism in more depth. Moreover, this has led to a greater appreciation of the interplay between the immune microenvironment and cancer cells in driving therapeutic response.

This Special Issue will encompass research that focuses on the intrinsic metabolic features of NSCLC, with the objective of bringing together the most novel research in the field. This will provide a comprehensive view of metabolism in NSCLC, offering a valuable tool for basic and translational scientists. We seek high-quality, original research and review papers on topics that include, but are not limited to; metabolic regulation of NSCLC, intrinsic metabolic rewiring of NSCLC, the interplay between the metabolism of NSCLC cells and the tumor microenvironment, novel therapeutic options targeting metabolism, biomarkers of response to therapeutics targeting metabolism, strategies to overcome resistance to metabolic drugs, advances in technology to study metabolism.

Dr. Catríona M. Dowling
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biomedicines is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • metabolic regulation of NSCLC
  • intrinsic metabolic rewiring of NSCLC
  • the interplay between the metabolism of NSCLC cells and the tumor microenvironment
  • novel therapeutic options targeting metabolism
  • biomarkers of response to therapeutics targeting metabolism
  • strategies to overcome resistance to metabolic drugs
  • advances in technology to study metabolism

Published Papers

This special issue is now open for submission.
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