Application of Liposomes in Cancer

Dear Colleagues,

Chemotherapy has a crucial role in cancer treatment; however, conventional cytotoxic drugs often lack specificity for targeting cancer cells. Additionally, many anticancer agents possess high toxicity, hydrophobic properties, and short half-lives, which limit their effectiveness in cancer therapy.  The emergence of nanotechnology has paved the way for the development of efficient nanoscale drug delivery systems, known as nanoparticles, for various diseases. Among these delivery systems, lipid-based nanoparticles, including natural lipid nanoparticles (exosomes) as well as synthetic nanoparticles (liposomes), have been shown to be very effective in demonstrating the ability to: (1) enhance cancer chemotherapy; (2) reduce the cytotoxicity of anticancer drugs to normal tissues, thereby reducing their toxic side effects; (3) increase the solubility of hydrophobic drugs; and (4) provide prolonged and controlled release of drugs.

This Special Issue of Biomedicines invites contributions (original research articles, reviews, and other relevant contributions) highlighting all newly developed and functionalized lipid nanoparticles for in vitro and in vivo applications. Elucidating their therapeutic strategies for cancer is of particular interest.

Dr. Shiyan Dong
Guest Editor

Manuscript Submission Information

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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biomedicines is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• liposomes
• lipid nanoparticles
• exosomes
• cancer treatment
• cancer diagnosis
• drug delivery
• active targeting