Feature Papers in Neuromodulation and Brain Stimulation

Dear Colleagues

Recent evidence reveals how the nervous system is involved in almost all physiological activities of the human body, from cardiorespiratory rhythm and inflammation to perception and consciousness. Consequently, the nervous system's role is fundamental for keeping the “health–disease” balance, resilience across life, and overall well-being. Neuromodulation includes a myriad of non-pharmacological therapeutic approaches that aim to modulate nervous system activity to restore maladaptive neuroplasticity associated with multiple conditions, such as chronic pain, neurodegenerative diseases, brain injury, mental health conditions, and inflammatory diseases. The main intervention types include transcranial electrical stimulation (tES), transcranial magnetic stimulation (TMS), spinal cord stimulation, nerve stimulation, and behavioral therapies such as meditation, mindfulness, mental imagery, and hypnosis. These techniques have shown positive effects on several medical conditions; however, their clinical validation, regulatory approval, and systematic use are still incipient, mainly due to unpowered studies, inappropriate parameter selection, and the lack of evidence integration. To accelerate the knowledge translation of neuromodulation, we must build a bridge between theoretical/technological development, clinical trial findings, meta-synthesis methods, and implementation strategies, including cost-effectiveness studies. A coherent and organized integration among these disciplines will foster neuromodulation translation to the clinic and unlock these therapies' real potential.

This Topical Collection aims to create a space for “cross-talk” between disciplines about the clinical translation of neuromodulatory techniques, from theoretical and basic neuromodulation models to clinical findings. We welcome original research papers, theoretical and methodology papers, and review papers describing the generation, use, and knowledge translation of neuromodulation, especially those exploring new technologies, precision medicine, transdiagnosis approach, and biomarkers.

Prof. Dr. Felipe Fregni
Dr. Kevin Pacheco-Barrios
Dr. Aurore Thibaut
Collection Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the collection website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biomedicines is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• neuromodulation
• non-pharmacological interventions
• neuropsychiatric conditions
• chronic pain
• brain injury
• computational models

• Neuromodulation from Theory to Therapy in Biomedicines (10 articles)