Epigenetics in Parathyroid Tumors

Dear Colleagues,

Parathyroid tumors are common forms of endocrine neoplasia. They are mainly benign lesions associated with parathormone (PTH) inappropriate secretion, determining the metabolic disorder known as primary hyperparathyroidism (PHPT). Parathyroid tumors are characterized by calcium-sensing receptor (CASR)-mediated reduced sensitivity to extracellular calcium. Accumulating evidence suggests that epigenetic factors play pivotal roles in parathyroid tumorigenesis. However, many aspects need to be explored, including the molecular pathways related to epigenetic aberrations and their effects on parathyroid cell proliferation and/or sensitivity to extracellular calcium.

Our Special Issue will focus on epigenetic features of parathyroid tumorigenesis, to provide potential novel targets for new therapeutic approaches or biomarkers supporting diagnosis. To this end, we wish to invite investigators from basic, pathophysiological, and clinical research to contribute with original articles, reviews, or communications.

Dr. Valentina Vaira
Dr. Sabrina Corbetta
Guest Editors

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• parathyroid disorders
• parathyroid adenomas
• parathyroid cancers
• epigenetics
• LncRNAs
• microRNAs
• circular RNAs
• DNA methylation
• DNA acetylation