Tumour Suppressor Genes: The Guardians of Cell Integrity

Dear Colleagues,

Cancer remains a major threat to individuals and a major challenge to healthcare systems worldwide. Tumour suppressor genes play a pivotal role in regulating cell proliferation and preventing tumour formation. For this reason, studying their mechanism of action and defining in detail the intracellular pathways they regulate become of massive importance for implementing patients’ therapy.

This Biomolecules Special Issue explores the intricate functions and critical roles of tumour suppressor proteins in the context of cancer biology. This Special Issue will explore the diverse mechanisms through which tumour suppressor proteins regulate fundamental cellular processes. Specifically, we plan to examine the complex interplay between tumour suppressor proteins and oncogenic pathways, highlighting their significance in cancer development, progression, and therapeutic targeting.

By shedding light on the multifaceted functions of tumour suppressor proteins, this Special Issue aims to deepen our understanding of cancer pathogenesis and pave the way for novel therapeutic strategies.

Dr. Nicola Manfrini
Guest Editor

Manuscript Submission Information

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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biomolecules is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• cell cycle
• cell growth
• cell integrity
• cell proliferation
• DNA damage
• genome integrity
• protein homeostasis
• migration
• invasion
• metastasis
• apoptosis
• autophagy