NAD Metabolism in Physiology and Pathology

Dear Colleagues,

Nicotinamide adenine dinucleotide (NAD) and its metabolites function as critical regulators to maintain cellular processes. Serving as a crucial co-enzyme for redox reactions and substrate for NAD-dependent enzymes, NAD and its metabolites act as a regulatory hub controlling a broad range of physiological processes, including redox homeostasis, genomic stability, gene expression, RNA processing, energy metabolism, immunity and inflammation, and the circadian clock. Given the essential roles of NAD in most biological processes, NAD metabolic abnormalities represent major contributors to the pathophysiology of various diseases, such as infections, cancers, metabolic diseases, aging, and age-associated neurodegenerative disorders.

This Special Issue aims to provide novel insights into NAD metabolism in physiology and pathology. We welcome original research and review articles on these topics.

Prof. Dr. Mathias Ziegler
Guest Editor

Manuscript Submission Information

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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biomolecules is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• NAD
• ADP-ribosylation
• sirtuins
• redox homeostasis
• NAD glycohydrolases