Cannabinoids in Neurobehavioral Modulation

Dear Colleagues,

Since the discovery first of the main phytocannabinoids of the cannabis plant and then of the main components of the endocannabinoid system, the wide distribution of this neuromodulatory system and its crucial involvement in the functional regulation of the central nervous system have become apparent. In this sense, there has been great interest in recent decades in identifying and understanding the role of the endocannabinoid system in physiological conditions and how it is altered in various psychiatric, neurological or addictive disorders. Similarly, much emphasis has been placed on understanding the effects of functional manipulation of this system through the use of both phytocannabinoids and synthetic cannabinoids, with a particular focus on the potential therapeutic benefits that could be derived for the treatment of brain diseases.

This Special Issue aims to collect original articles or reviews (narrative or systematic) that mainly focus on the neurobehavioural actions derived from the use of cannabinoid compounds, from a translational point of view, by collecting preclinical data. Special attention will be given to manuscripts that provide relevant information from a therapeutic perspective on the use of cannabinoid compounds in the context of different disorders of the nervous system, as well as those related to the effects of cannabis use at different stages of life, in view of the increasing and worrying use worldwide, especially in vulnerable populations such as adolescents or pregnant women.

Dr. Francisco Navarrete
Prof. Dr. María S. García Gutiérrez 
Guest Editors

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• cannabinoids
• neurobehavior
• brain diseases
• therapeutic
• translational

Title: cannabinoids and psychotic-like behavior
Authors: Ester Aso
Affiliation: Universitat de Barcelona, Barcelona, Spain

Title: CBD and neuroinflammation in female rats in a rat model for PTSD
Authors: IRIT AKIRAV; Anna Portugalov
Affiliation: School of Psychological Sciences, University of Haifa, Israel