Molecular Mechanisms and Biomedical Applications of Virus Entry

Dear Colleagues,

Understanding the mechanistic details of viral entry is vital to prevent early stages of virus infection. The process of viral entry starts when viral proteins interact specifically with the cell surface receptor, resulting in the virus–host cell membrane fusion. In this dynamic process, several host cell factors, including cell surface heparan sulfate, act as critical components to facilitate viral entry. It is believed that cell types, the expression of cell surface receptors, changes in viral strain all influence viral entry, suggesting the persisting challenges in the field. In this Special Issue, we welcome submissions of research or review articles on recent advances in our understanding of viral entry, virus tropism, and virus entry-mediated signaling pathways, including host cellular factors affecting the entry of either DNA and or RNA viruses. Further topics include heparan sulfate signaling, novel compound targeting viral entry and viral entry exploiting the host cell cytoskeleton.

Dr. Vaibhav Tiwari
Guest Editor

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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• heparan sulfate
• virus entry
• virus–host cell interactions
• virus cell-to-cell fusion