DNAzyme-Based Biosensors

Dear Colleagues,

In recent years, DNAzymes have gained recognition as a powerful tool for the development of biosensors in a wide range of fields. Emerging applications in the biosensor sciences include on-site detection, point-of-care diagnostics, and non-invasive cellular and tissue imaging. DNAzymes can be obtained through in vitro selection in a test tube to deliver high affinity for a target of interest, high selectivity against interfering targets, and rapid target binding. DNAzymes can be rationally designed for biosensors, which allow the exploitation of the complementarity of DNA for controlled capture and release, as well as the incorporation of isothermal nucleic acid-based signal amplification strategies. The development of DNAzyme-based biosensors with high sensitivity, reproducible results, and stability has become a hot topic in recent years.

For this Special Issue, we welcome original research papers as well as reviews on current developments in the design of highly sensitive, selective, and reproducible DNAzyme-based biosensors. This includes the design of state-of-the-art biosensors for disease biomarkers, characterisation of biomolecules, biological analysis, and medical diagnostics. Theoretical research related to DNAzymes’ structure or function is also encouraged. The design and development of lab-on-a-chip devices, wearable and plug-and-play biosensors, and portable/handheld DNAzyme-based biosensors for point-of-care applications and DNAzyme-based bioimaging systems is of special interest. Reviews should provide an in-depth examination of the most recent research in a specific context or discuss the current and future issues related to DNAzymes in the biosensor field.

Dr. Yuan Ma
Dr. Quanbing Mou
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biosensors is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• DNAzyme
• biosensor
• bioimaging
• analytical chemistry