Genetic and Epigenetic Heterogeneity in Cancer

A special issue of Cancers (ISSN 2072-6694). This special issue belongs to the section "Molecular Cancer Biology".

Deadline for manuscript submissions: 31 May 2025 | Viewed by 338

Special Issue Editor

Department of Cancer Biology, Wake Forest University, Winston-Salem, NC 27157, USA.
Interests: epigenetics; genomics; clinicogenomics; post-transcriptional regulation; non-small-cell lung cancer
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Cancer remains a formidable challenge, continuously pushing the boundaries of our comprehension regarding its fundamental mechanisms and, consequently, our capacity to combat it effectively. The traditional perspective on cancer as a uniform disease is rapidly transforming, giving way to a more intricate understanding of its profound heterogeneity. The striking diversity in cancer phenotypes bears testimony to the intricate interplay of genetic mutations, epigenetic modifications, and microenvironmental factors, collectively shaping the trajectory of the disease. Unraveling this heterogeneity is essential not just for a comprehensive grasp of cancer but also for tailoring effective therapeutic strategies.

In this Special Issue, we embark on a journey into the intricate world of "Genetic and Epigenetic Heterogeneity in Cancer". We have curated a collection of articles that delve deeply into the genetic and epigenetic dimensions of cancer heterogeneity. Through a series of comprehensive reviews, original research contributions, and thought-provoking commentaries, this Special Issue aspires to reveal the underlying factors driving the diverse forms of cancer, underscore the epigenetic nuances contributing to cancer heterogeneity, explore the clinical implications linking genetic and epigenetic heterogeneity, especially in terms of prognosis and treatment responses, and spotlight innovative technologies and methodologies facilitating a more profound exploration of the genetic and epigenetic complexities in cancer. These advancements offer hope for potential breakthroughs.

The knowledge presented in this Special Issue is a testament to the ever-evolving nature of cancer research, where new discoveries and innovations continuously reshape our understanding and treatment strategies. We trust that this compilation of articles will serve as an inspiration for researchers, clinicians, and all stakeholders in the field to persist in their pursuit of unraveling the mysteries of cancer, bringing us one step closer to more effective therapies and, ultimately, a world where the burden of cancer is significantly alleviated.

Dr. Liang Liu
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cancers is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • genetics
  • epigenetics
  • cancer heterogeneity
  • cancer diagnosis
  • cancer treatment

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Published Papers

This special issue is now open for submission.
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