New Advances and Challenges for Radiotherapy of Gastrointestinal Malignancies

A special issue of Cancers (ISSN 2072-6694). This special issue belongs to the section "Cancer Therapy".

Deadline for manuscript submissions: closed (30 June 2024) | Viewed by 244

Special Issue Editor


E-Mail Website
Guest Editor
Radiation Oncology Unit, “SS Annunziata” Hospital, 66100 Chieti, Italy
Interests: radiotherapy; gastrointestinal tumors

Special Issue Information

Dear Colleagues,

Gastrointestinal (GI) tumors are leading cause of cancer-related mortality and remain a big challenge for cancer treatment. The role of radiotherapy in multidisciplinary treatment of GI malignancies is well recognized, also in curative treatment of elderly patients. Advances in imaging, radiotherapy planning and delivery techniques as well as the integration with novel drugs have made it possible to improve clinical oncological outcomes with better quality of life, less adverse events and more organ reserving strategies. The role of intensity-modulated radiotherapy and stereotactic body radiotherapy is grown for many GI malignancies. Modern imaging techniques, in particular, magnetic resonance imaging and positron emission tomography scans have been progressively used in radiotherapy planning and to assess treatment response. Moreover, integrated MRI-linear accelerator systems (MR-linacs) can adapt the treatment based on daily changes in shape, size and position of the tumor and surrounding tissue and to increase the accuracy of treatment delivery. Finally, molecular biomarkers and radiomics have been investigated as predictors of prognosis and response to radiotherapy. Despite these advances a fair number of patients still develop distant metastases and therapy resistance, and new therapeutic strategies are then now required to improve the prognosis of GI cancers. The current issue aims to increase our knowledge to achieve these goals.

We are pleased to invite you for both original research and review articles that highlight recent advances in the followed (but are not limited to) fields of research in gastrointestinal cancer:
1. Advances in the curative multimodal management.
2. Treatment options for elderly patients.
3. Organ preservation strategies and “watch and wait” approach.
4. Integration of Immunotherapy and Target therapies with radiotherapy.
5. The role of MRI in radiotherapy: from staging to delivery and response evaluation and prediction.

We look forward to receiving your contributions.

Dr. Luciana Caravatta
Guest Editor

Manuscript Submission Information

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Keywords

  • gastrointestinal cancer
  • esophageal cancer
  • pancreatic cancer
  • colorectal cancer
  • anal cancer
  • biomarkers
  • magnetic resonance imaging
  • radiomics
  • immunotherapy
  • particle therapy

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Published Papers

There is no accepted submissions to this special issue at this moment.
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