Prostate Cancer—from Molecular Mechanisms to Clinical Care
A topical collection in Cancers (ISSN 2072-6694). This collection belongs to the section "Molecular Cancer Biology".
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Interests: precision medicine; patients stratification; prostate cancer; molecular signatures; androgen receptor; MYC; bromodomain; chromatin; transcriptomics; single cell; gene regulation; radiobiology
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Topical Collection Information
Dear Colleagues,
Prostate cancer is the second leading cause of cancer-related death in men worldwide.
The treatment options for men with advanced form of the disease have been focused on targeting the androgen receptor signaling axes for decades. Recent technical developments that allow better resolution have increased our understanding of the molecular mechanisms that are important for prostate cancer biology and disease evolution.
As new, possibly druggable, targets are discovered and novel treatment options enter clinical trials, the need to improve the link between molecular discoveries and clinical management also increases.
This Collection will focus on the current status and challenges in treating early and progressive prostate cancer, covering topics from basic research and technical developments to specific new and emerging targets, and the clinical management of prostate cancer patients.
Dr. Alfonso Urbanucci
Dr. Delila Gasi Tandefelt
Collection Editors
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Keywords
- prostate cancer
- castration resistance
- neuroendocrine prostate cancer
- personalized medicine
- precision medicine
- molecular medicine
- liquid biopsies
- cancer biomarkers
- cancer screening
- PSA
- androgens
- androgen receptor