Physiology and Pathology
A section of Life (ISSN 2075-1729).
Section Information
This section of the journal Life rapidly and rigorously publishes contributions related to the health and disease of living cells, tissues, and organisms. Starting from a cellular and tissue perspective, the broad focus of this section also covers the emerging properties of the human organism system, including human behavior and motor control. Human diseases are another area of interest for this section. This aspect is investigated both from a pathophysiological and clinical perspective. Clinical application consequences are also of interest.
This section upholds high standards in terms of facts, ethics, and relevance from both a research and clinical application perspective. Topics include, but are not limited to, the following:
- Applied physiology
- Biomechanics
- Cardiovascular pathobiology
- Cell physiology
- Comparative pathology
- Comparative physiology
- Computational physiology and medicine
- Defense physiology
- Environmental pathology
- Exercise physiology
- Human behavior
- Integrative physiology
- Molecular physiology
- Motor control
- Neurophysiology
- Organismal physiology
- Pediatric pathology
- Pathobiology
- Pathophysiology
- Physiome
- Systems physiology
- Vascular pathophysiology
Editorial Board
Topical Advisory Panel
Special Issues
Following special issues within this section are currently open for submissions:
- Translational Neuro-Oncology: Molecular Insights, Bioinformatics, and Technological Innovations (Deadline: 20 September 2026)
- Mitochondrial and Endoplasmic Reticulum Dynamics in Cellular Stress Responses (Deadline: 25 September 2026)
- From Physiology and Pathology Research to Clinical Insights in Gastrointestinal Disorders (Deadline: 30 September 2026)
- Pathophysiology, Diagnosis, and Treatments of Intestinal Diseases—2nd Edition (Deadline: 30 September 2026)
- Research Updates in Hematology (Deadline: 30 September 2026)
- From Vessel to Muscle—an Integrative Approach to Ischemic Heart Disease (Deadline: 15 October 2026)
- Outlook for Cerebrovascular Damage Research (Deadline: 15 October 2026)
- Encephalitis: From Molecular Pathophysiology to Therapy (Deadline: 30 October 2026)
- Organ Predilection of Certain Gastrointestinal Diseases—Pathophysiology, Diagnosis and Management (Deadline: 30 October 2026)
- Research Progress in Kidney Diseases (Deadline: 30 October 2026)
- Metabolic Reprogramming in Cancers: Vulnerabilities and Therapeutic Exploitation (Deadline: 30 October 2026)
- Innovative Applications of Extracellular Vesicles: From Diagnostics to Drug Delivery (Deadline: 31 October 2026)
- Novel Insights into Biomarkers and Molecular Mechanisms in Heart Failure (Deadline: 31 October 2026)
- The Roles and Regulation of RECK in Cell Behavior, Animal Development, and Diseases (Deadline: 31 October 2026)
- Interdisciplinarity in Cardiovascular Diseases: From Pathophysiology to Diagnosis and Treatment—4th Edition (Deadline: 31 October 2026)
- Pathological Mechanisms of Heart Failure with Preserved Ejection Fraction (Deadline: 31 October 2026)
- Exploring the Mechanisms of the Effects of Microplastics and Nanomaterials on Biological Physiological Functions (Deadline: 31 October 2026)
- The Role of Mitochondrial Function in Cancer and Diseases and Therapeutic Explorations (Deadline: 31 October 2026)
- Environmental and Microbial Stressors in Neuronal Dysfunction: Mechanistic Insights (Deadline: 31 October 2026)
- Immunopathology of Oral Mucosal Disease (Deadline: 15 November 2026)
- Preload, Afterload and Diastolic Heart Disease (Deadline: 15 November 2026)
- Gut Microbiome and Neurodegenerative Disease (Deadline: 15 November 2026)
- Advances in Assessment and Treatment of Human Motor and Sensory Dysfunctions (Deadline: 30 November 2026)
- Mitochondrial Transplantation: Therapeutic Strategies and Applications (Deadline: 30 November 2026)
- Cellular Inflammation and Regeneration: Mechanisms and Therapeutic Targets (Deadline: 30 November 2026)
- From Environmental Exposure to Health Effects: Advances in Toxicology and Biomonitoring (Deadline: 30 November 2026)
- Microvascular and Macrovascular Response in Healthy and Critically Ill (Deadline: 30 November 2026)
- The Brain-Boosting Power of Exercise: Improving Cerebrovascular and Cognitive Health (Deadline: 30 November 2026)
- Nutrition, Exercise and Stress (Deadline: 30 November 2026)
- The 15th Anniversary of Life: Endothelial Glycocalyx—a Determinant of Endothelial Function and Vascular Reactivity (Deadline: 11 December 2026)
- Multifaceted Role of Tryptophan-Kynurenine Pathway in Metabolism and Human Health: From Molecular Targets to Therapeutic Interventions (Deadline: 20 December 2026)
- Advances in Computational and Spatial Pathology (Deadline: 20 December 2026)
- Kidney Disease: From Pathophysiology to Personalized Approaches (Deadline: 30 December 2026)
- New Insights into Cell Death Mechanisms and Multi-Omics in Cancer (Deadline: 30 December 2026)
- Common and Novel Markers of Inflammation and Tissue Damage in Various Pathological Conditions—2nd Edition (Deadline: 31 December 2026)
- Advances in Metabolic Associated Fatty Liver Disease: Pathophysiology, Diagnosis, and Emerging Therapies (Deadline: 31 December 2026)
- Chronic Pain: From Molecular Mechanisms to Targeted Interventions (Deadline: 31 December 2026)
- New Updates in Adipocytes and Adipose Tissue—3rd Edition (Deadline: 31 December 2026)
- Nutrition and Human Gut Health: Mechanisms, Disease Pathogenesis, and Future Perspectives (Deadline: 31 December 2026)
- Effects of Exercise Training on Muscle Function—2nd Edition (Deadline: 31 December 2026)
- The 15th Anniversary of Life—Recent Advances in Pancreatic Beta Cell Physiology (Deadline: 31 December 2026)
- Precision Medicine and Tumor Microenvironment in Colorectal Cancer: Genetics, Biomarkers, and Personalized Models (Deadline: 31 December 2026)
- Advances in Headache Research: Pathophysiology, Molecular Mechanisms, and Data-Driven Approaches (Deadline: 31 December 2026)
- Physical Activity, Inflammation, and Adipocytokines: Molecular Responses in Health and Disease (Deadline: 31 December 2026)
- Melatonin Signaling: Therapeutic Implications and Molecular Mechanisms (Deadline: 31 December 2026)
- Neuromechanics and Precision Motor Control for Functional Health (Deadline: 20 January 2027)
- Gynecological Endocrinology: From Physiological Mechanisms to Clinical Practice: 2nd Edition (Deadline: 31 January 2027)
- Advanced Research in Exercise Medicine (Deadline: 31 January 2027)
- Management of Chronic Kidney Disease and Its Comorbidities (Deadline: 31 January 2027)
- Biological Determinants of Physical Function and Vascular Health: From Molecular Mechanisms to Clinical Outcomes (Deadline: 31 January 2027)
- Mechanisms of Environmental Toxicant-Induced Disruption of Physiological Homeostasis (Deadline: 31 January 2027)
- Understanding Early Dysmetabolism in Adolescents: Bridging Research, Mechanisms and Clinical Management (Deadline: 31 January 2027)
- Current and Future Perspectives of Takotsubo Syndrome (Deadline: 31 January 2027)
- Advances in Knee Biomechanics—2nd Edition (Deadline: 15 February 2027)
- Neuroimaging and Integrative Analyses in Psychiatry and Addictive Disorders (Deadline: 15 February 2027)
- Lipid Metabolism and Cellular Stress Pathways in Cancer, Normal Tissue Injury and Therapeutic Response (Deadline: 16 February 2027)
- Health Effects of Environmental Exposure to Contaminants (Deadline: 20 February 2027)
- Clinical Updates on Cardiovascular Health: From Pathophysiology to Precision Medicine (Deadline: 26 February 2027)
- Physiological, Pathological, and Clinical Effects of Exercise Training and Physical Activity (Deadline: 28 February 2027)
- Methylglyoxal and Glycative Stress in Health, Aging and Disease (Deadline: 28 February 2027)
- Move to Thrive: Pioneering Health and Resilience Through Physical Activity (Deadline: 28 February 2027)
- Extracellular Vesicles: Biology, Mechanisms, and Therapies for Cerebrovascular Disorders (Deadline: 28 February 2027)
- The Nexus of Redox Signaling, Metabolism, and Mitochondrial Function in Cardiovascular Diseases (Deadline: 20 March 2027)
- Epigenetics, Microbiota, and Food—Shaping Immune Health and Longevity (Deadline: 31 March 2027)
- Prostate Cancer: From Molecular Insights to Clinical Applications (Deadline: 31 March 2027)
- Pathogenesis, Biomarkers, and Targeted Therapeutic Strategies Across Multiple Human Malignancies (Deadline: 31 March 2027)
- Neural Mechanisms of Brain–Computer Interfaces (Deadline: 31 March 2027)
- Immune Regulation in Tissue Repair and Regeneration (Deadline: 18 April 2027)
- Regulation of Cerebrovascular Resistance in Health and Disease: From Molecules to Humans: 2nd Edition (Deadline: 26 April 2027)
- Advances and Applications of Sport Physiology: 2nd Edition (Deadline: 30 April 2027)
- Compulsive Disorder: Understanding of the Pathophysiology and Therapeutic Implications (Deadline: 30 April 2027)
- Microvascular Dynamics, Architecture, and Function (Deadline: 30 April 2027)
- Ferroptosis in Human Disease: Molecular Mechanisms, Biomarkers, and Therapeutic Opportunities (Deadline: 30 April 2027)
- Nutrition, Metabolism and Fitness: Exploring Dietary Effects on Exercise Physiology (Deadline: 31 May 2027)
- Skin Care and Innovation from the Perspective of Molecular Dermatology (Deadline: 31 May 2027)
- Ophthalmologic Diseases: From Molecules and Molecular Mechanisms to Therapeutics (Deadline: 30 June 2027)
- Emerging Therapeutic Strategies for Fibrosis: From Molecular Mechanisms to Drug Discovery (Deadline: 31 December 2027)