Special Issues

Life publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

Section
Search by Title/Keyword
 
Order results
Display
Results per page
Advances in Diagnostic Imaging for Systemic Disorders
edited by Christoph Strolz
submission deadline 29 Dec 2025 | Viewed by 209
Keywords: high-resolution computed tomography (HRCT); diffusion-weighted imaging (DWI); dual-energy CT in musculoskeletal imaging; high-resolution ultrasonography; SPECT/CT; PET/CT modalities
(This special issue belongs to the Section Radiobiology and Nuclear Medicine)
Current Views on Knee Osteoarthritis: 3rd Edition submission deadline 30 Dec 2025 | 2 articles | Viewed by 8034 | Submission Open
Keywords: knee osteoarthritis; metabolic syndrome; obesity; pathogenesis; adipokines; disease-modifying; treatment; personalized medicine
(This special issue belongs to the Section Medical Research)
Advances in Neural Stem Cell Medicine
edited by Kiminobu Sugaya
submission deadline 30 Dec 2025 | Viewed by 193 | Submission Open
Keywords: neural stem cell; neurodegenerative diseases; cell therapy; exosomes
(This special issue belongs to the Section Physiology and Pathology)
Gastrointestinal Health: Clinical Research and Therapeutic Innovations
edited by
submission deadline 31 Dec 2025 | 22 articles | Viewed by 53382 | Submission Open
Keywords: gut microbiota; inflammatory bowel diseases; irritable bowel syndrome; gastroesophageal reflux disease; fatty liver disease; liver cirrhosis; probiotics; mediterranean diet; epidemiology; diagnosis; treatment; artificial intelligence
(This special issue belongs to the Section Medical Research)
Cystic Fibrosis: A Disease with a New Face
edited by and Patricia A. Walker
submission deadline 31 Dec 2025 | 16 articles | Viewed by 48837 | Submission Open
Keywords: cystic fibrosis; CFTR modulator; CF newborn screening; CF nutrition; lung transplant in CF; CF family planning
(This special issue belongs to the Section Medical Research)
Plant Biotic and Abiotic Stresses 2024
edited by and
submission deadline 31 Dec 2025 | 24 articles | Viewed by 40295 | Submission Open
Keywords: plant stress; abiotic stress; biotic stress
(This special issue belongs to the Section Plant Science)
New Trends in Otorhinolaryngology submission deadline 31 Dec 2025 | 10 articles | Viewed by 35296 | Submission Open
Keywords: head and neck; otolaryngology; hearing loss; speech disorders; swallowing disorders; cancer; microRNA; nose; plastic surgery
(This special issue belongs to the Section Medical Research)
Clinical Management and Prevention of Adverse Pregnancy Outcomes submission deadline 31 Dec 2025 | 6 articles | Viewed by 26874 | Submission Open
Keywords: pathologic pregnancies; ultrasound; clinical and molecular characteristics; fetal pathologies
(This special issue belongs to the Section Reproductive and Developmental Biology)
New Diagnostic and Therapeutic Developments in Eye and Systemic Diseases
edited by
submission deadline 31 Dec 2025 | 8 articles | Viewed by 25078 | Submission Open
Keywords: eye diseases; systemic diseases; oculomics; ocular imaging; eye surgery; retina; cornea; glaucoma; refractive surgery; OCT; OCTA
(This special issue belongs to the Section Medical Research)
New Insights into Breast Cancer: Current Controversies and Future Perspectives
edited by , Angela Bucaro and Flavia de Lauretis
submission deadline 31 Dec 2025 | 11 articles | Viewed by 21522 | Submission Open
Keywords: breast cancer treatment; oncoplastic surgery; conservative mastectomy; breast reconstruction; sentinel node biopsy; chemotherapy; radiotherapy; integrated therapies
(This special issue belongs to the Section Medical Research)
Advances in Non-Alcoholic Fatty Liver Disease: Pathophysiology, Diagnosis, and Emerging Therapies submission deadline 31 Dec 2025 | 4 articles | Viewed by 18559 | Submission Open
Keywords: non-alcoholic fatty liver disease (NAFLD); metabolic dysfunction-associated fatty liver disease (MAFLD); steatohepatitis; metabolic syndrome; insulin resistance; apoptosis/cell death
(This special issue belongs to the Section Medical Research)
Obstetrics and Gynecology Medicine: From Bench to Bedside—2nd Edition submission deadline 31 Dec 2025 | 10 articles | Viewed by 15133 | Submission Open
Keywords: obstetrics; gynecology; translational research; translational medicine
(This special issue belongs to the Section Medical Research)
Trends in Clinical Research 2025 submission deadline 31 Dec 2025 | 4 articles | Viewed by 13505 | Submission Open
Keywords: artificial intelligence; biomedical research; digital health; evidence-based medicine; health policy; new therapies; new drugs; patient-centered research; personalized medicine; translational medicine
(This special issue belongs to the Section Medical Research)
Ecology and Conservation of Small Mammals: Exploring Biodiversity, Climate Resilience, and Ecosystem Dynamics Through Small Mammal Monitoring and Research: 2nd Edition submission deadline 31 Dec 2025 | 8 articles | Viewed by 13219 | Submission Open
Keywords: small mammals; biodiversity; indicators; monitoring; assessment; communities
(This special issue belongs to the Section Diversity and Ecology)
Advances in Non-Invasive Brain Stimulation submission deadline 31 Dec 2025 | 2 articles | Viewed by 9132 | Submission Open
Keywords: translational neuroscience; clinical neurophysiology; neurodegeneration; neural plasticity; neurosonology; sleep disorders; cognitive decline; non-invasive brain stimulation; nutraceuticals; neurogenetics; transcranial magnetic stimulation; dementia; vascular cognitive impairment; stroke; depression; metaplasticity; motor cortex; motor learning; neurotrophins; transcranial-focused ultrasound
(This special issue belongs to the Section Medical Research)
Recent Advances in Functional Genomics
edited by Katerina R. Katsani and
submission deadline 31 Dec 2025 | 3 articles | Viewed by 8327 | Submission Open
Keywords: chromatin profiling; CRISPR screens; crop genomics; epigenome editing; epigenomics; interactomes; metagenomics; pharmacogenomics; phenomics
(This special issue belongs to the Section Genetics and Genomics)
Mechanism, Diagnostic and Therapeutic Novelties in Dermatology: 3rd Edition
edited by Jose Carlos Armario Hita, and
submission deadline 31 Dec 2025 | 2 articles | Viewed by 7996 | Submission Open
Keywords: physiopathology; skin sonography; dermoscopy; innovation; confocal microscopy; biological treatment; psoriasis; atopic dermatitis; inmmunomediated diseases; urticaria; laser CO2
(This special issue belongs to the Section Medical Research)
Plant Physiology: From Omic Analysis Toward Physiological Mechanism Research: 2nd Edition
edited by and Fang He
submission deadline 31 Dec 2025 | 3 articles | Viewed by 6444 | Submission Open
Keywords: plant physiology; transcriptome; proteomics; gene regulatory network; bioinformation; omics; molecular mechanisms
(This special issue belongs to the Section Plant Science)
Molecular Biomarkers in Inflammatory Diseases
edited by Stelvio Tonello
submission deadline 31 Dec 2025 | 2 articles | Viewed by 5817 | Submission Open
Keywords: cytokines; chemokines; and immune mediators as pharmacodynamic biomarkers; genomic and epigenomic contributions to drug response variability; proteomic and metabolomic profiling to guide pharmacotherapy in inflammation; biomarker-driven strategies for drug development and personalized treatment; mechanistic studies on drug– biomarker interactions and their clinical relevance; novel biomarkers for predicting adverse drug reactions in inflammatory diseases
(This special issue belongs to the Section Medical Research)
Molecular Mechanisms of Preeclampsia
edited by Feng Li
submission deadline 31 Dec 2025 | 2 articles | Viewed by 5346 | Submission Open
Keywords: preeclampsia; hypertension; proteinuria; placenta; fetal growth restriction; pregnancy com-plications; implantation
(This special issue belongs to the Section Reproductive and Developmental Biology)
Bioactive Compounds for Medicine and Health submission deadline 31 Dec 2025 | 3 articles | Viewed by 5023 | Submission Open
Keywords: phytochemistry; bioactive compounds; cancer; immune modulation; heart disease; diabetes; obesity; neurodegenerative diseases; neuroprotection
(This special issue belongs to the Section Pharmaceutical Science)
Pain: New Insights into Mechanisms, Diagnosis, Therapy, and Management
edited by and I-Han Hsiao
submission deadline 31 Dec 2025 | 2 articles | Viewed by 3955 | Submission Open
Keywords: pain; mechanisms; signaling pathways; diagnosis
(This special issue belongs to the Section Physiology and Pathology)
The Biology and Functions of Platelets: Emerging Challenges
edited by and Miriam Andrea Duque
submission deadline 31 Dec 2025 | 3 articles | Viewed by 3867 | Submission Open
Keywords: platelet; hemostasis; toll-like receptor; immunity; phagocytosis; transfusions; von Willebrand factor; thrombocyte
(This special issue belongs to the Section Medical Research)
Feature Papers in Animal Science: 4th Edition
edited by
submission deadline 31 Dec 2025 | 3 articles | Viewed by 3855 | Submission Open
Keywords: fish; microbial ecology; lipid nutrition; electron microscopy; gut microbiota; proteomics; next-generation sequencing; arthropod parasites; protease inhibitors; disease vectors; cystatin; serpin; Kunitz; tick; insect; vector– host interaction; innate immunity; shellfish immunology; bivalve molluscs; transcriptomics; diseases; hemocytes; microscopy
(This special issue belongs to the Section Animal Science)
The Emerging Clinical Relevance of Artificial Intelligence, Data Science, and Wearable Devices in Headache
edited by , , Muneto Tatsumoto and Shingo Shimoda
submission deadline 31 Dec 2025 | 1 articles | Viewed by 3514 | Submission Open
Keywords: headache; migraine; tension-type headache; trigeminal autonomic cephalalgias; medication-overuse headache; primary headaches; secondary headaches; raising awareness; calcitonin gene-related peptide (CGRP) monoclonal antibodies; artificial intelligence; wearable devices; data sciences
(This special issue belongs to the Section Medical Research)
Synthetic Genetic Elements, Devices, and Systems: 2nd Edition
edited by and
submission deadline 31 Dec 2025 | 2 articles | Viewed by 2958 | Submission Open
Keywords: synthetic biology; synthetic genetic elements/parts; biobricks; artificial gene synthesis; biocomputing; directed evolution; metabolic engineering/cell factory; optogenetics; genetic code expansion; xenobiology
(This special issue belongs to the Section Synthetic Biology and Systems Biology)
Diagnosis and Treatment of Erectile Dysfunction
edited by
submission deadline 31 Dec 2025 | 1 articles | Viewed by 2711 | Submission Open
Keywords: erectile dysfunction; non-invasive methods; surgical strategies
(This special issue belongs to the Section Physiology and Pathology)
From Muscle to Fascia: Current Trends and Future Perspectives submission deadline 31 Dec 2025 | 1 articles | Viewed by 2375 | Submission Open
Keywords: connective tissue; deep fascia; superficial fascia; retinacula; muscle stiffness; hyaluronan; densification; biomechanics; therapies
(This special issue belongs to the Section Physiology and Pathology)
Neurobiological and Neuroepigenetic Factors in Childhood Disorders: Autism Spectrum Disorder and Obesity
edited by Elisa Na
submission deadline 31 Dec 2025 | 1 articles | Viewed by 2293 | Submission Open
Keywords: obesity; autism spectrum disorder; hypothalamus; cerebellum; frontal cortex; epigenetics
(This special issue belongs to the Section Physiology and Pathology)
Traumatic Brain Injury: Epidemiology, Diagnosis, Treatment and Biomarkers submission deadline 31 Dec 2025 | 1 articles | Viewed by 1843 | Submission Open
Keywords: traumatic brain injury; neurotrauma; epidemiology; rehabilitation; neurological disorders; biomarkers
(This special issue belongs to the Section Physiology and Pathology)
Language Models in Lab Coats: AI-Powered Biomedical Interpretation
edited by Sebastian Sanduleanu
submission deadline 31 Dec 2025 | 1 articles | Viewed by 1729 | Submission Open
Keywords: radiology; large language models; artificial intelligence; radiobiology
(This special issue belongs to the Section Medical Research)
Advancing Cancer Radiodiagnostics Through Artificial Intelligence: Techniques, Applications, and Challenges
edited by Pei-Ju Chao, , and
submission deadline 31 Dec 2025 | 1 articles | Viewed by 1642 | Submission Open
Keywords: artificial intelligence; cancer radiodiagnostics; machine learning; tumor detection; radiomics integration
(This special issue belongs to the Section Medical Research)
Advancements in Heart Failure Research: 2nd Edition
edited by Tzu-Hurng Cheng, and
submission deadline 31 Dec 2025 | 1 articles | Viewed by 1479 | Submission Open
Keywords: cardiac remodeling; biomarkers; precision medicine; patient-centered care; therapeutic innovations
(This special issue belongs to the Section Physiology and Pathology)
Advances in Artificial Intelligence for Medical Image Analysis: 2nd Edition
edited by
submission deadline 31 Dec 2025 | 1 articles | Viewed by 1394 | Submission Open
Keywords: artificial intelligence; medical imaging; deep learning for medical imaging; histopathological image analysis; medical diagnosis; visualization in biomedical imaging; magnetic resonance imaging (MRI); X-ray computed tomography (CT); positron emission tomography (PET); medical image fusion
(This special issue belongs to the Section Medical Research)
Update on Clinical Pharmacology
edited by
submission deadline 31 Dec 2025 | 1 articles | Viewed by 1374 | Submission Open
Keywords: drug efficacy and drug safety; new drug development; therapeutic drug monitoring; clinical trials; pharmacodynamic and pharmacokinetics; pharmacovigilance; clinical toxicology
(This special issue belongs to the Section Pharmaceutical Science)
Characterization, Bioactivity Evaluation and Utilization of Plant Polysaccharides
edited by and
submission deadline 31 Dec 2025 | 1 articles | Viewed by 1304 | Submission Open
Keywords: plant polysaccharides; identification; characterization; functional property; biological activity; health benefit; food packaging
(This special issue belongs to the Section Pharmaceutical Science)
Research Updates in Hematology
edited by
submission deadline 31 Dec 2025 | 1 articles | Viewed by 1043 | Submission Open
Keywords: antiphospholipid syndrome; complement; endothelium; hemoglobinopathies; hemophilia; leukemias; lymphomas; multiple myeloma; pediatric hematology; thrombosis
(This special issue belongs to the Section Physiology and Pathology)
Topographical Anatomy and Physiological Mechanics of the Musculoskeletal System submission deadline 31 Dec 2025 | 1 articles | Viewed by 647 | Submission Open
Keywords: muscle; bone; joint; peripheral nerve; motor innervation; proprioception; anatomical variant; radiologic imaging; development; comparative anatomy
(This special issue belongs to the Section Medical Research)
The Interactions Between Cells and Their Microenvironment
edited by and
submission deadline 31 Dec 2025 | Viewed by 545 | Submission Open
Keywords: cell microenvironment; extracellular matrix; interstitial cells
(This special issue belongs to the Section Cell Biology and Tissue Engineering)
Radiological Diagnosis of Cervical Spondylosis and Carotid Artery Disease
edited by Anusha Vaddi
submission deadline 31 Dec 2025 | Viewed by 443 | Submission Open
Keywords: carotid artery disease; atherosclerosis; cervical spondylosis; c-spine; radiological diagnosis; diagnostic accuracy; AI in radiology
(This special issue belongs to the Section Medical Research)
Early Prebiotic Reaction Networks
edited by Olga Taran and Paul J. Bracher
submission deadline 31 Dec 2025 | Viewed by 392 | Submission Open
Keywords: thioesters; autocatalytic reactions; redox cycling; chemical fossils; TCA cycle analogues
(This special issue belongs to the Section Origin of Life)
Sustainable Agroforestry: Molecular Strategies for Integrated Pest and Disease Management
edited by Gothandapani Sellamuthu and Kanakachari Mogilicherla
submission deadline 31 Dec 2025 | Viewed by 323 | Submission Open
Keywords: sustainable agroforestry; integrated pest management; genomics; transcriptomics; CRISPR technology; RNAi; plant– microbe interactions; biopesticides
(This special issue belongs to the Section Plant Science)
Plant Adaptation Mechanisms to Abiotic Stresses
edited by Sunchung Park and Ezekiel Ahn
submission deadline 31 Dec 2025 | Viewed by 310 | Submission Open
Keywords: abiotic stress; plant adaptation mechanisms; cold; heat; drought; salinity; flooding; waterlogging; transcription factors
(This special issue belongs to the Section Plant Science)
Origin of Life in Chemically Complex Messy Environments: 3rd Edition submission deadline 31 Dec 2025 | Viewed by 284 | Submission Open
Keywords: origin of life; complex chemical systems  ; prebiotic chemistry  ; prebiotic metabolisms  ; chemical evolution  ; prebiotic catalysts
(This special issue belongs to the Section Origin of Life)
Coagulation and Its Disorders: Diagnostics, Therapeutics, and Clinical Management submission deadline 31 Dec 2025 | Viewed by 281 | Submission Open
Keywords: coagulation; bleeding disorders; disseminated intravascular coagulation; fibrinolysis; new diagnostic tools and treatment; inflammation and coagulation disorders; thrombosis; platelet disorders; coagulation alterations induced by hepatic and metabolic disorders; drug-induced coagulation alterations
Understanding Brain Disorders Through EEG and AI submission deadline 31 Dec 2025 | Viewed by 276 | Submission Open
Keywords: EEG; ADHD; Alzheimer’ s; Parkinson’ s; neurological disorders; machine learning; deep learning
(This special issue belongs to the Section Radiobiology and Nuclear Medicine)
Artificial Intelligence in Cardiovascular Diseases: Research, Technology and Clinical Practice
edited by
submission deadline 31 Dec 2025 | Viewed by 272 | Submission Open
Keywords: cardiovascular disease; artificial intelligence; atherosclerosis; atrial fibrillation; cardiomyopathy
(This special issue belongs to the Section Medical Research)
Recent Advances in Left Ventricular Unloading Therapy
edited by Mehmet Oezkur
submission deadline 31 Dec 2025 | Viewed by 145 | Submission Open
Keywords: left ventricular unloading therapy; cardiovascular medicine; heart failure; acute myocardial infarction
(This special issue belongs to the Section Medical Research)
Research on Female Reproductive Health and Metabolism
edited by
submission deadline 31 Dec 2025 | Viewed by 138 | Submission Open
Keywords: female reproduction; metabolism; nutrition; adipose tissue; hypothalamus– pituitary– gonadal axis; insulin resistance; adipocytokines; reproductive disorders; PCOS
(This special issue belongs to the Section Physiology and Pathology)
Biochemical Modulators in Chronic Diseases: The Antioxidant/Anti-Inflammatory Interdependence—2nd Edition
edited by
submission deadline 31 Dec 2025 | Viewed by 108 | Submission Open
Keywords: oxidative stress; inflammation; redox modulator; anti-inflammatory agents; chronic diseases; antioxidant paradox; reactive oxygen species
(This special issue belongs to the Section Pharmaceutical Science)
Back to TopTop