Multifunctional Coatings for Bone Regenerative Medicine (Volume II)

Dear Colleagues,

The aging of the population is resulting in millions of people undergoing implant surgery for total hip and knee replacement, scoliosis, maxillofacial fixation, and traumatic conditions. However, many of these implants fail due to (1) implant loosening due to lack of the necessary new bone formation to repair large bone defects or suitable integration with the existing bone and (2) implant-associated infection, in spite of novel engineering designs, sterilized operating theatre environments, and prophylaxis antibiotic therapy. To overcome these issues, different surface modification and coating strategies have been explored for decades. However, a significant challenge remains in developing optimal biofunctionalized implants, mainly because they offer only a single functionality (either enhanced bone regeneration or antibacterial). On the other hand, because of recent progress in additive manufacturing technologies, which are allowing researchers to design and fabricate rationally designed and topologically complex structures, it is now possible to introduce biomaterials with unprecedented combinations of mechanical, physical, and biological properties. Therefore, it is essential to focus on further developments in a new generation of biomaterials that offer multiple functionalities, including enhanced bone regeneration, and infection prevention, in addition to rendering bespoke release profiles of active agents to address unmet clinical needs.

This Special Issue aims to highlight the recent strategies in multifunctional coatings for bone regenerative medicine application. It is our pleasure to invite you to contribute your research articles, communications, or reviews to this Special Issue.

Dr. Saber AminYavari
Guest Editor

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• multifunctional coatings
• implant-associated infection
• osseointegration
• regenerative medicine
• additive manufacturing