Interactions between Probiotics and Host

Dear Colleagues,

As a result of rich microbial biodiversity, a group of beneficial organisms was widely studied. Probiotics are classically characterized as microorganisms that, when administered in adequate amounts, promote the health of their hosts. Through interactions with microbiota and epithelial surfaces, these microorganisms regulate the expression of multiple genes in their hosts, triggering responses that bring the sick body to homeostasis, promoting health and well-being. Applied in animal and cellular models, it has been observed that different probiotic strains are able to change the course of infections, the inflammation of mucous membranes and the skin, autoimmune diseases, and colorectal cancer, in addition to regulating nutrient absorption, the gut–brain axis, etc. Some mechanisms associated with these beneficial effects have already been described and could involve the regulation and maintenance of microbiota homeostasis, the protection of mucous membranes and skin, the promotion of epithelial barrier functions, and stimulation of the immune system, modulating inflammatory responses at local and systemic levels.

This Special Issue aims to assemble original research articles and reviews that address interactions between probiotic strains and hosts, highlighting their beneficial effects in different contexts of diseases or dysbiosis-dependent diseases. Research areas may include (but are not limited to) the following: mucosal and non-mucosal microbiota, gastroenterology, neurosciences, dermatology, immunology, and human and animal nutrition.

I look forward to receiving your contributions.

Prof. Dr. Sávio Henrique De Cicco Sandes
Guest Editor

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• probiotics
• postbiotics
• dysbiosis
• beneficial microbes
• gastroenterology diseases
• skin
• gut–brain axis
• mucosal and systemic immunology
• mucosal barrier
• microbiome