Applications of Crystal Engineering in Drug Delivery

Dear Colleagues,

Manuscripts are invited for publication in a Special Issue of Pharmaceutics entitled "Applications of Crystal Engineering in Drug Delivery". This Special Issue is focused on the use of crystal engineering methods to improve drug properties such as solubility and dissolution rate for optimum drug delivery.  Crystal engineering is a broad area of research that included crystal habit modification, polymorphism, solid dispersions, and salt formation.  All these pre-formulation and formulation techniques entail that the drug can be modified using methods such as solvent evaporation or dry methods such as mechanochemical activation.  Often, the drug properties can be significantly altered when the crystalline structure is altered or even completely vanish, such as in the case of amorphous form formation.  The outcome of such modifications affects physical properties and can have a dramatic impact on physiological properties, such as bioavailability and absorption.  Drug delivery applications include various routes, such as oral, pulmonary, ophthalmic, buccal, vaginal, transdermal, and parenteral drug delivery. Recent advances in this area of research have shown potential application of these techniques to use crystal engineering to achieve targeted drug delivery for novel molecules such as anticancer drugs, antimicrobials, and vaccines. 

Dr. Hisham Al-Obaidi
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-anonymized peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Pharmaceutics is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.