Nanomedicine and Thrombolytics – Present and Future Partnership to Overcome Thrombotic Related Diseases

A special issue of Pharmaceutics (ISSN 1999-4923). This special issue belongs to the section "Nanomedicine and Nanotechnology".

Deadline for manuscript submissions: closed (30 October 2021) | Viewed by 326

Special Issue Editors


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Guest Editor
Department of Systems Pharmacology and Translational Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA
Interests: targeted nanoparticles; drug delivery systems; neurovascular inflammation; thrombosis and hemostasis; gene therapy

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Guest Editor
Institute of Molecular Medicine, University of Lisbon Faculty of Medicine, Lisbon, Portugal
Interests: antimicrobial proteins; blood clot function; drug delivery systems

Special Issue Information

Dear Colleagues,

Presently, ischemia and stroke caused by thrombosis are treated by using intravenous tissue plasminogen activator (IV-tPA) and thrombectomy approach. However, there are several drawbacks in using these approaches, as IV-tPA must be used within 4.5 h of disease onset, with possible major haemorrhagic effects. Moreover, thrombectomy is an invasive approach that may lead to vascular damage.

In order to improve the therapeutic window and prophylactic treatments on identified patients at risk of thrombosis-related diseases, nanomedicine has been employed in both new drug design and drug improvement or repurposing.

This Special Issue of Pharmaceutics will cover the developments in thrombolytics and nanomedicine intervention in thrombosis-related diseases as a new road to be explored for targeted and improved therapeutics.

Dr. Oscar Marcos-Contreras
Dr. Marco Domingues
Guest Editors

Manuscript Submission Information

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Keywords

  • thrombolytics
  • nanomedicine
  • antithrombotic
  • pulmonary embolism
  • stroke
  • venous thromboembolism

Published Papers

There is no accepted submissions to this special issue at this moment.
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