Pesticides in Formulations: Toxicological and Regulatory Assessments, New Developments

Dear Colleagues,

It appears to most of us that the long-term effects of pesticides in ecosystems need to be better understood and their use regulated. New discoveries regarding the compositions of fully marketed formulations with components other than the declared active ingredients are poorly studied and rarely taken into account when establishing admissible daily intakes, for instance. Comparisons of the effects of pesticides used in the environment versus those of the declared active ingredients alone are rarely studied; however, this is crucial to shed light on the real toxicity of pesticides.

The aim of this Special Issue is to explain new discoveries, particularly regarding the long-term toxicities of pesticides in whole ecosystems, and, importantly, how these are taken into consideration by health and regulatory agencies. The scope is to understand the new developments in the knowledge of full formulations, especially compared to the known effects of the declared active ingredients alone. The understanding of the nature and toxicities of formulants other than the declared active ingredients will be of interest. The major pesticides of the world, i.e., glyphosate-based herbicides, which are being debated in all continents, will be focused on.

Any knowledge in various sciences helping to understand this topic is welcome; even reviews and technical, biological, epidemiological, sociological, theoretical, historical or multidisciplinary approaches are encouraged. How was the regulation of pesticides established and how has it evolved? How quickly are new discoveries regarding undeclared or poorly declared components of the formulations used by humans, and mixtures in foods or the natural environment, considered? What is the difference between the effects of the mixtures and those of the declared active ingredients alone at a biological, population or molecular level? We will try to address these questions and related ones.

We look forward to receiving your contributions. If you are interested, please indicate if you could send us the manuscript this year.

Prof. Dr. Gilles-Eric Seralini
Guest Editor

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