Development of Vaccines for Zoonotic Diseases

Dear Colleagues,

This Special Issue focuses on recent advancements in the development of vaccines for zoonotic diseases. This issue will include both disease specific advancements, as well as novel vaccine technologies and platforms.

Zoonotic diseases comprise about 60% of new infectious diseases worldwide. The development and use of vaccines for zoonotic diseases can arguably be the most important countermeasure in the battle against zoonosis. The obvious goal is to prevent disease morbidity and mortality. However, vaccines also represent a cost-effective tool to prevent economic losses for both human and animal populations, ameliorate barriers to international trade and to establish transmission barriers between domestic animals, wildlife and humans.

While in some countries the prevalence of vaccination, and associated diagnosis, epidemiology and control of zoonotic infections is very good for other countries these issues remain partially or fully unresolved. There is a need to enhance both traditional and novel strategies for the effective development, production, distribution and administration of cheap effective zoonotic disease vaccines.

Important vaccination strategies should also be considered which include the vaccination of humans to prevent or attenuate disease transmission to animals, methods to effectively vaccinate wildlife to prevent transmission to important domestic animals and or humans or strategies to effectively vaccinate both animal and human populations. The development of effective vaccines, which can be administered to both animal and human populations is an understudied area of vaccinology and represents a tremendous opportunity for a true One Health approach for zoonotic diseases. An important aspect of vaccines, that has been previously described, is their ability to generate herd immunity which protects both vaccinates and non-vaccinate/non-responders. The development and use of multi-species vaccines has the potential to protect a much larger and more diverse herd within the animal kingdom.

Dr. Jeffrey J. Adamovicz
Guest Editor

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• vaccines
• zoonotic diseases
• vaccine platforms
• animal models
• correlates of immunity
• vaccine efficacy
• vaccinology
• One Health