Revised NMR data for Incartine: an Alkaloid from Galanthus elwesii
Abstract
:Introduction
Results and Discussion
Position | Η δ (J in Hz) | COSY | NOESY | HMQC | HMBC |
---|---|---|---|---|---|
1 | 4.46 br s | H-2 | H-2, H-10, H-10b, 2-OCH3 | 67.7 d | C-2, C-3, C4a |
2 | 3.85 overlapped | H-1 | H-1, H-3, H-4a, 2-OCH3 | 78.2 d | C-1, C-4, C-10b, 2-OCH3 |
3 | 3.48 brd d (1.0) | - | H-2, H-11β, 2-OCH3 | 59.0 d | C-1, C-2 |
4 | 66.9 s | ||||
4a | 2.56 d (11.2) | H-10b | H-2, H-10b | 61.3 d | C-3, C-4, C-6, C-10a |
6α | 3.65 dd (14.0, 1.0) | H-6β | H-6β, H-7, H-12α | 56.7 t | C-4a, C-6a, C-7, C-12 |
6β | 4.07 d (14.0) | H-6α | H-6α, H-7, H-12β | 56.7 t | C-4a, C-6a, C-7 |
6a | 128.5 s | ||||
7 | 6.57 s | H-6α, H-6β, 8-OCH3 | 110.7 d | C-6, C-8, C-9,C-10a, 8-OMe | |
8 | 147.8 s | ||||
9 | 147.9 s | ||||
10 | 6.78 s | H-1, 9-OCH3 | 107.6 d | C-6a, C-8, C-9, C-10b | |
10a | 127.9 s | ||||
10b | 2.82 d (11.2) | H-4a | H-1, H-4a, 2-OCH3 | 40.1 d | C-4a, C-10a |
11α | 2.00 ddd (14.5, 6.5, 2.0) | H-11β, H-12α, H-12β | H-11β, H-12α | 30.1 t | C-3, C-4, C-12 |
11β | 2.39 ddd (14.5, 10.3, 7.5) | H-11α, H-12α, H-12β | H-3, H-11α, H-12β | 30.1 t | C-4, C-4a, C-12 |
12α | 2.59 ddd (10.3, 9.0, 6.5) | H-11α, H-11β, H-12β | H-6α, H-11α, H-12β | 53.0 t | C-4, C-6 |
12β | 3.20ddd (9.0, 7.5, 2.0) | H-11α, H-11β, H-12α | H-6β, H-11β, H-12α | 53.0 t | C-4, C-4a, C-11 |
2-OMe | 3.54 s | H-1, H-2, H-3, H-10b | 59.2 q | C-2 | |
8-OMe | 3.80 s | H-7 | 56.1 q | C-8 | |
9-OMe | 3.84 s | H-10 | 56.2 q | C-9 |
Experimental
General
Plant material
Extraction and isolation
Bioactivity assays
Acknowledgments
References
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Berkov, S.; Reyes-Chilpa, R.; Codina, C.; Viladomat, F.; Bastida, J. Revised NMR data for Incartine: an Alkaloid from Galanthus elwesii. Molecules 2007, 12, 1430-1435. https://doi.org/10.3390/12071430
Berkov S, Reyes-Chilpa R, Codina C, Viladomat F, Bastida J. Revised NMR data for Incartine: an Alkaloid from Galanthus elwesii. Molecules. 2007; 12(7):1430-1435. https://doi.org/10.3390/12071430
Chicago/Turabian StyleBerkov, Strahil, Ricardo Reyes-Chilpa, Carles Codina, Francesc Viladomat, and Jaume Bastida. 2007. "Revised NMR data for Incartine: an Alkaloid from Galanthus elwesii" Molecules 12, no. 7: 1430-1435. https://doi.org/10.3390/12071430