Synthesis of Novel Benzimidazolyl-substituted Acrylonitriles and Amidino-substituted Benzimidazo[1,2-a]Quinolines
Abstract
:Introduction
Results and Discussion
Comp. | λmax/nm | ε x 103 (dm3mol-1 cm-1) | λemiss/nm | λexc/nm | Int (arb. un.) |
---|---|---|---|---|---|
3 | 355 280 | 21.7 8.4 | 445 | 352 280 | 28.6 |
4 | 371 278 | 17.6 12.1 | 490 | 367 274 | 570.0 |
5 | 387 351 270 | 6.4 9.9 35.5 | 469 | 350 268 245 | 864.5 |
6 | 370 276 | 7.9 32.5 | 507 | 370 274 247 | 126.3 |
7 | 375 344 267 | 7.8 4.6 28.9 | 467 | 345 268 240 | 469.5 |
8 | 374 276 | 8.1 35.2 | 507 | 368 272 249 | 121.1 |
Conclusions
Experimental
General
General method for preparation of 3 and 4.
2-(1H-benzimidazol-2-yl)-3-acrylonitrile (3)
2-(1H-benzimidazol-2-yl)-3-(4-cyanophenyl)-acrylonitrile (4)
General method for preparation of 5 and 6
Benzimidazo[1,2-a]quinoline-6-carbonitrile (5)
Benzimidazo[1,2-a]quinoline-2,6-dicarbonitrile (6)
General method for preparation of benzimidazo[1,2-a]quinoline-6-carboxamide 7 and 2-amidino-benzimidazo[1,2-a]quinoline-6-carboxamides 8-10
Benzimidazo[1,2-a]quinoline-6-carboxamide (7)
2-Carboxamidine-benzimidazo[1,2-a]quinoline-6-carboxamide hydrochloride (8)
2-(1H-imidazol-2-yl)-benzimidazo[1,2-a]quinoline-6-carboxamide Hydrochloride (9)
N-Morpholin-4-yl-benzimidazo[1,2-a]quinoline-6-carboxamide hydrochloride (10)
Acknowledgements
References
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Hranjec, M.; Karminski-Zamola, G. Synthesis of Novel Benzimidazolyl-substituted Acrylonitriles and Amidino-substituted Benzimidazo[1,2-a]Quinolines. Molecules 2007, 12, 1817-1828. https://doi.org/10.3390/12081817
Hranjec M, Karminski-Zamola G. Synthesis of Novel Benzimidazolyl-substituted Acrylonitriles and Amidino-substituted Benzimidazo[1,2-a]Quinolines. Molecules. 2007; 12(8):1817-1828. https://doi.org/10.3390/12081817
Chicago/Turabian StyleHranjec, Marijana, and Grace Karminski-Zamola. 2007. "Synthesis of Novel Benzimidazolyl-substituted Acrylonitriles and Amidino-substituted Benzimidazo[1,2-a]Quinolines" Molecules 12, no. 8: 1817-1828. https://doi.org/10.3390/12081817