Synthesis of Seco-Chlorinated Derivatives of Phenanthroindolizidine Precursors via Friedel-Crafts Reaction
Abstract
:1. Introduction
2. Results and Discussion
3. Experimental
3.1. General
3.2. Synthesis of N-(3,6-dihydroxy-2,7-dimethoxyphenanthr-9-ylmethyl)-2-chloromethylpyrrolidine (3a)
3.3. Synthesis of N-(4,10-dichloro-3-hydroxy-2,6,7-trimethoxyphenanthr-9-ylmethyl)-2-chloro methylpyrrolidine (4) and N-(4-chloro-3-hydroxy-2,6,7-trimethoxyphenanthr-9-ylmethyl)-2-chloromethylpyrrolidine (5).
4. Conclusions
Acknowledgements
References and Notes
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Sample Availability: Samples of the compounds 4 and 5 are available from the authors. |
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Li, S.; Han, L.; Liu, J.; Hu, Y.; Zheng, D.; Fu, Y.; Huang, X. Synthesis of Seco-Chlorinated Derivatives of Phenanthroindolizidine Precursors via Friedel-Crafts Reaction. Molecules 2010, 15, 8501-8506. https://doi.org/10.3390/molecules15118501
Li S, Han L, Liu J, Hu Y, Zheng D, Fu Y, Huang X. Synthesis of Seco-Chlorinated Derivatives of Phenanthroindolizidine Precursors via Friedel-Crafts Reaction. Molecules. 2010; 15(11):8501-8506. https://doi.org/10.3390/molecules15118501
Chicago/Turabian StyleLi, Songtao, Li Han, Jiang Liu, Yihan Hu, Dan Zheng, Yingbo Fu, and Xueshi Huang. 2010. "Synthesis of Seco-Chlorinated Derivatives of Phenanthroindolizidine Precursors via Friedel-Crafts Reaction" Molecules 15, no. 11: 8501-8506. https://doi.org/10.3390/molecules15118501