Antiproliferative Activity, Antioxidant Capacity and Tannin Content in Plants of Semi-Arid Northeastern Brazil
Abstract
:1. Introduction
2. Results and Discussion
2.1. Antioxidant activity
2.2. Tannin content
2.3. Antiproliferative activities
3. Experimental
3.1. Plant selection
3.2. Preparation of extracts
3.3. Determination of tannins
3.4. Antiproliferative activity
3.5. Quantification of antioxidant activity using the DPPH method (2,2-diphenyl-2-picrylhydrazyl)
4. Conclusions
Acknowledgements
References
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Sample Availability: Available from the authors. |
Family/ Species (Voucher number) | Type/ part used | Antioxidant activity (IC50 in µg/mL) | Tannin content (mg/100 mg) | Percentage of living cells in the HEp-2 cell line (%) | Percentage of living cells in the NCI-H292 cell line (%) |
---|---|---|---|---|---|
Annonaceae | |||||
Annona muricata L. (50480) | tree/ leaves | 221.52 ± 16.12 | ND | 54.92 ± 1.44 | 24.94 ± 0.74 |
Asteraceae | |||||
Ageratum conyzoides L. (50478) | herb/ aerial parts | 340.17 ± 31.94 | ND | 81.45 ± 0.85 | 105.14 ± 3.34 |
Delilia biflora (L.) Kuntze (50477) | herb/ aerial parts | 533.02 ± 31.92 | ND | 58.19 ± 2.49 | 77.37 ± 1.05 |
Bignoniaceae | |||||
Handroanthus impetiginosus (Mart. ex DC.) Mattos (50481) | tree/ leaves | 173.17 ± 16.56 | ND | 45.73 ± 2.19 | 41.8 ± 0.47 |
Cyperaceae | |||||
Cyperus distans L. f. (50487) | herb/ aerial parts | 258.42 ± 15.29 | 1.22 ± 0.02 | 132.09 ± 7.99 | 102.03 ± 1.71 |
Euphorbiaceae | |||||
Croton blanchetianus Baill. (48667) | shrub/ leaves | 94.41 ± 2.67 | 2.13 ± 0.09 | 103.56 ± 3.88 | 94.29 ± 3.96 |
Jatropha mollissima (Pohl) Baill. (48661) | shrub/ leaves | 54.09 ± 4.36 | 2.35 ± 0.08 | 142.06 ± 5.06 | 88.32 ± 0.3 |
Fabaceae | |||||
Amburana cearensis (Allemão) A.C. Sm. (50486) | tree/ leaves | 203.14 ± 6.83 | 1.55 ± 0.11 | 94.58 ± 4.31 | 103.74 ± 1.32 |
Anadenanthera colubrina (Vell.) Brenan (48663) | tree/ leaves | 73.24 ± 1.47 | 4.41 ± 0.47 | 117.32 ± 1.76 | 97.24 ± 0.89 |
Poincianella pyramidalis (Tul.) L. P. Queiroz (48662) | tree/ leaves | 42.95 ± 1.77 | 8.17 ± 0.64 | 90.97 ± 0.94 | 105.46 ± 0.97 |
Crotalaria incana L. (50485) | shrub/ leaves | 1123.28 ± 153.21 | ND | 115.39 ± 2.06 | 102.73 ± 2.23 |
Senna occidentalis (L.) Link (50484) | shrub/ leaves | 628.27 ± 85.14 | ND | 103.37 ± 1.61 | 99.42 ± 0.77 |
Loasaceae | |||||
Mentzelia aspera L. (50483) | herb/ aerial parts | 911.5 ± 166.39 | ND | 45.61 ± 1.94 | 86.04 ± 0.35 |
Verbenaceae | |||||
Lantana camara L. (50479) | shrub/ leaves | 114.63 ± 6.16 | ND | 55.98 ± 0.74 | 25.08 ± 0.19 |
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Gomes de Melo, J.; De Sousa Araújo, T.A.; Thijan Nobre de Almeida e Castro, V.; Lyra de Vasconcelos Cabral, D.; Do Desterro Rodrigues, M.; Carneiro do Nascimento, S.; Cavalcanti de Amorim, E.L.; De Albuquerque, U.P. Antiproliferative Activity, Antioxidant Capacity and Tannin Content in Plants of Semi-Arid Northeastern Brazil . Molecules 2010, 15, 8534-8542. https://doi.org/10.3390/molecules15128534
Gomes de Melo J, De Sousa Araújo TA, Thijan Nobre de Almeida e Castro V, Lyra de Vasconcelos Cabral D, Do Desterro Rodrigues M, Carneiro do Nascimento S, Cavalcanti de Amorim EL, De Albuquerque UP. Antiproliferative Activity, Antioxidant Capacity and Tannin Content in Plants of Semi-Arid Northeastern Brazil . Molecules. 2010; 15(12):8534-8542. https://doi.org/10.3390/molecules15128534
Chicago/Turabian StyleGomes de Melo, Joabe, Thiago Antônio De Sousa Araújo, Valérium Thijan Nobre de Almeida e Castro, Daniela Lyra de Vasconcelos Cabral, Maria Do Desterro Rodrigues, Silene Carneiro do Nascimento, Elba Lúcia Cavalcanti de Amorim, and Ulysses Paulino De Albuquerque. 2010. "Antiproliferative Activity, Antioxidant Capacity and Tannin Content in Plants of Semi-Arid Northeastern Brazil " Molecules 15, no. 12: 8534-8542. https://doi.org/10.3390/molecules15128534
APA StyleGomes de Melo, J., De Sousa Araújo, T. A., Thijan Nobre de Almeida e Castro, V., Lyra de Vasconcelos Cabral, D., Do Desterro Rodrigues, M., Carneiro do Nascimento, S., Cavalcanti de Amorim, E. L., & De Albuquerque, U. P. (2010). Antiproliferative Activity, Antioxidant Capacity and Tannin Content in Plants of Semi-Arid Northeastern Brazil . Molecules, 15(12), 8534-8542. https://doi.org/10.3390/molecules15128534