Relationship between Oversulfation and Conformation of Low and High Molecular Weight Fucoidans and Evaluation of Their in Vitro Anticancer Activity
Abstract
:1. Introduction
2. Results and Discussion
3. Experimental
3.1. Extraction, hydrolysis and fractionation of fucoidan
3.2. Proximate composition and in vitro anticancer activity
4. Conclusions
Acknowledgements
References
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Sample Availability: Oversulfated fucoidans from U. pinnatifida are available from the authors. |
Sample | F5-30k (%) | F>30k (%) |
---|---|---|
Native fucoidan | 35.5 ± 1.9 | 31.7 ± 2.2 |
Oversulfated fucoidan | 56.8 ± 2.3 | 41.2 ± 0.9 |
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Cho, M.L.; Lee, B.-Y.; You, S.G. Relationship between Oversulfation and Conformation of Low and High Molecular Weight Fucoidans and Evaluation of Their in Vitro Anticancer Activity. Molecules 2011, 16, 291-297. https://doi.org/10.3390/molecules16010291
Cho ML, Lee B-Y, You SG. Relationship between Oversulfation and Conformation of Low and High Molecular Weight Fucoidans and Evaluation of Their in Vitro Anticancer Activity. Molecules. 2011; 16(1):291-297. https://doi.org/10.3390/molecules16010291
Chicago/Turabian StyleCho, Myoung Lae, Boo-Yong Lee, and Sang Guan You. 2011. "Relationship between Oversulfation and Conformation of Low and High Molecular Weight Fucoidans and Evaluation of Their in Vitro Anticancer Activity" Molecules 16, no. 1: 291-297. https://doi.org/10.3390/molecules16010291