Molecular Docking Characterization of a Four-Domain Segment of Human Fibronectin Encompassing the RGD Loop with Hydroxyapatite
Abstract
:1. Introduction
2. Results and Discussion
2.1. Identification of Potential HAP-Binding Sites on FN-III7–10 Surface and Molecular Docking of HAP to FN
2.2. Analysis of HAP-Binding Site on RGD Loop
3. Experimental
3.1. Setup of FN-III7–10 and HAP Structures
3.2. The FN-III7–10 Binding Site Prediction with MPK2
3.3. Performing Molecular Docking with AutoDock 4
4. Conclusions
Acknowledgments
Conflicts of Interest
References
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Guo, T.; Kang, W.; Xiao, D.; Duan, R.; Zhi, W.; Weng, J. Molecular Docking Characterization of a Four-Domain Segment of Human Fibronectin Encompassing the RGD Loop with Hydroxyapatite. Molecules 2014, 19, 149-158. https://doi.org/10.3390/molecules19010149
Guo T, Kang W, Xiao D, Duan R, Zhi W, Weng J. Molecular Docking Characterization of a Four-Domain Segment of Human Fibronectin Encompassing the RGD Loop with Hydroxyapatite. Molecules. 2014; 19(1):149-158. https://doi.org/10.3390/molecules19010149
Chicago/Turabian StyleGuo, Tailin, Wenyuan Kang, Dongqin Xiao, Rongquan Duan, Wei Zhi, and Jie Weng. 2014. "Molecular Docking Characterization of a Four-Domain Segment of Human Fibronectin Encompassing the RGD Loop with Hydroxyapatite" Molecules 19, no. 1: 149-158. https://doi.org/10.3390/molecules19010149