Structure–Activity Relationship of Oligomeric Flavan-3-ols: Importance of the Upper-Unit B-ring Hydroxyl Groups in the Dimeric Structure for Strong Activities
Abstract
:1. Introduction
2. Results and Discussion
2.1. DPPH Radical Scavenging Activity
2.2. Antimicrobial Activity against S. cerevisiae
2.3. Cervical Epithelioid Carcinoma Cell Line, HeLa S3 Proliferation Inhibitory Activity
3. Experimental Section
3.1. General Information
3.2. Synthesis
3.3. DPPH Radical Scavenging Activity
3.4. Antimicrobial Activity against S. cerevisiae
3.5. Inhibitory Activity of HeLa S3 Cell Proliferation
4. Conclusions
Acknowledgments
Author Contributions
Conflicts of Interest
References
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Hamada, Y.; Takano, S.; Ayano, Y.; Tokunaga, M.; Koashi, T.; Okamoto, S.; Doi, S.; Ishida, M.; Kawasaki, T.; Hamada, M.; et al. Structure–Activity Relationship of Oligomeric Flavan-3-ols: Importance of the Upper-Unit B-ring Hydroxyl Groups in the Dimeric Structure for Strong Activities. Molecules 2015, 20, 18870-18885. https://doi.org/10.3390/molecules201018870
Hamada Y, Takano S, Ayano Y, Tokunaga M, Koashi T, Okamoto S, Doi S, Ishida M, Kawasaki T, Hamada M, et al. Structure–Activity Relationship of Oligomeric Flavan-3-ols: Importance of the Upper-Unit B-ring Hydroxyl Groups in the Dimeric Structure for Strong Activities. Molecules. 2015; 20(10):18870-18885. https://doi.org/10.3390/molecules201018870
Chicago/Turabian StyleHamada, Yoshitomo, Syota Takano, Yoshihiro Ayano, Masahiro Tokunaga, Takahiro Koashi, Syuhei Okamoto, Syoma Doi, Masahiko Ishida, Takashi Kawasaki, Masahiro Hamada, and et al. 2015. "Structure–Activity Relationship of Oligomeric Flavan-3-ols: Importance of the Upper-Unit B-ring Hydroxyl Groups in the Dimeric Structure for Strong Activities" Molecules 20, no. 10: 18870-18885. https://doi.org/10.3390/molecules201018870