Silymarin Constituents Enhance ABCA1 Expression in THP-1 Macrophages
Abstract
:1. Introduction
2. Results and Discussion
2.1. Impact of the Studied Components of Silymarin on THP-1 Cell Viability
2.2. Impact of Isosilybin A on Cholesterol Efflux
2.3. Impact of the Active Components of Silymarin on ABCA1 Protein Expression
3. Materials and Methods
3.1. Chemicals, Cell Culture Reagents and Antibodies
3.2. Sources of the Compounds
3.3. Cell Culture
3.4. Resazurin Conversion Assay
3.5. ABCA1 Protein Quantification
3.6. Cholesterol Efflux Assay
3.7. Statistical Analysis
4. Conclusions
Acknowledgments
Author Contributions
Conflicts of Interest
References
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- Sample Availability: Not available.
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Wang, L.; Rotter, S.; Ladurner, A.; Heiss, E.H.; Oberlies, N.H.; Dirsch, V.M.; Atanasov, A.G. Silymarin Constituents Enhance ABCA1 Expression in THP-1 Macrophages. Molecules 2016, 21, 55. https://doi.org/10.3390/molecules21010055
Wang L, Rotter S, Ladurner A, Heiss EH, Oberlies NH, Dirsch VM, Atanasov AG. Silymarin Constituents Enhance ABCA1 Expression in THP-1 Macrophages. Molecules. 2016; 21(1):55. https://doi.org/10.3390/molecules21010055
Chicago/Turabian StyleWang, Limei, Susanne Rotter, Angela Ladurner, Elke H. Heiss, Nicholas H. Oberlies, Verena M. Dirsch, and Atanas G. Atanasov. 2016. "Silymarin Constituents Enhance ABCA1 Expression in THP-1 Macrophages" Molecules 21, no. 1: 55. https://doi.org/10.3390/molecules21010055