Synthetic Procedures Leading towards Aminobisphosphonates
Abstract
:1. Introduction
2. Overview of Synthetic Procedures
2.1. Synthesis from Carboxylic Acids
2.2. Synthesis from Amides
2.3. Synthesis from Nitriles
2.4. Synthesis from Isonitriles
2.5. Synthesis via Ketophosphonates
2.6. Three-Component Condensation of Amines with Triethyl Orthoformate and Diethylphosphite
2.7. Addition of Amines to Vinylidenebisphosphonates
2.8. Miscellaneous Procedures
3. Functionalization of Aminobisphosphonates
3.1. Direct Acylation of Aminobisphosphonic Acids
3.2. Direct Acylation of Tetraethyl Aminobisphosphonates
3.3. Synthesis of Building Blocks for Polymer Chemistry
3.4. Miscellaneous
4. Conclusions
Acknowledgments
Conflicts of Interest
References
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Chmielewska, E.; Kafarski, P. Synthetic Procedures Leading towards Aminobisphosphonates. Molecules 2016, 21, 1474. https://doi.org/10.3390/molecules21111474
Chmielewska E, Kafarski P. Synthetic Procedures Leading towards Aminobisphosphonates. Molecules. 2016; 21(11):1474. https://doi.org/10.3390/molecules21111474
Chicago/Turabian StyleChmielewska, Ewa, and Paweł Kafarski. 2016. "Synthetic Procedures Leading towards Aminobisphosphonates" Molecules 21, no. 11: 1474. https://doi.org/10.3390/molecules21111474