Recent Advances in Substrate-Controlled Asymmetric Cyclization for Natural Product Synthesis
Abstract
:1. Introduction
2. Anionic Cyclizations
3. Cationic Cyclizations
4. Transition Metal-Mediated Cyclizations
5. Pericyclic Reactions
6. Radical Cyclizations
7. Conclusions
Acknowledgments
Author Contributions
Conflicts of Interest
Abbreviations
Ac | Acetyl |
AIBN | Azobisisobutyronitrile |
Bn | Benzyl |
Boc | t-Butoxycarbonyl |
Bu | Butyl |
Bz | Benzoyl |
cod | 1,5-Cyclooctadiene |
CSA | Camphorsulfonic acid |
dba | Dibenzylideneacetone |
DBU | 1,8-Diazabicyclo[5.4.0]undec-7-ene |
DCE | 1,2-Dichloroethane |
DDQ | 2,3-Dichloro-5,6-dicyano-1,4-benzoquinone |
DMDO | Dimethyldioxirane |
DMF | N,N-Dimethylformamide |
dppb | 1,4-Bis(diphenylphosphino)butane |
Et | Ethyl |
HMPA | Hexamethylphosphoramide |
IBX | o-Iodoxybenzoic acid |
LDA | Lithium diisopropylamide |
LED | Light emitting diode |
LHMDS | Lithium bis(trimethylsilyl)amide |
Me | Methyl |
MS | Molecular sieves |
Ms | Mesyl |
Ph | Phenyl |
PMB | 4-Methoxybenzyl |
PPTS | Pyridinium p-toluenesulfonate |
Pr | Propyl |
Py | Pyridine |
TBDPS | t-Butyldiphenylsilyl |
TBS | t-Butyldimethylsilyl |
TES | Triethylsilyl |
THF | Tetrahydrofuran |
TMS | Trimethylsilyl |
Ts | p-Toluenesulfonyl |
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Jo, J.; Kim, S.-H.; Han, Y.T.; Kwak, J.-H.; Yun, H. Recent Advances in Substrate-Controlled Asymmetric Cyclization for Natural Product Synthesis. Molecules 2017, 22, 1069. https://doi.org/10.3390/molecules22071069
Jo J, Kim S-H, Han YT, Kwak J-H, Yun H. Recent Advances in Substrate-Controlled Asymmetric Cyclization for Natural Product Synthesis. Molecules. 2017; 22(7):1069. https://doi.org/10.3390/molecules22071069
Chicago/Turabian StyleJo, Jeyun, Seok-Ho Kim, Young Taek Han, Jae-Hwan Kwak, and Hwayoung Yun. 2017. "Recent Advances in Substrate-Controlled Asymmetric Cyclization for Natural Product Synthesis" Molecules 22, no. 7: 1069. https://doi.org/10.3390/molecules22071069